LA eaRe bagore EI a a ge NICAL NATIONAL INSTITUTES OF”HEALTH “i L " - CLINI : ‘s wh oy ue oe * ae ow STAFF , . . Annals of Interna} Medicine . - Woman. There was also localized metastasis "into a lymph node. Subsequent studies after _ complete ablation of her thyroid gland have revealed no indication of metastases. The earlier cases of thyroid abnormalities have been previously described (10, 13). I would like now to say a few words about thyroid abnormalities as related to growth retardation in the children. As I indicated earlier, we had long been puzzled as to why these children had shown a slight _ degree of retardation in growth. We knew ‘that the Japanese children had been re- ported to have someslight retardation, particularly the male Japanese children at Hiroshima, but that picture was confused by such factors as physical and psychic trauma andnutritional deficiencies. Wefelt for any direct effect on epiphyseal growth. wae eB P. re Bam obey4 pe Fe ARE hat Ficure 13. Section showing invasion by metastatic papillary and follicular carcinoma of the thyroid into blood vessel (Case 6#). (Elastic, x 100.) eng+ : a “ a eeoe, Ficure 12. Microscopic section of nodule in Fig- ure 7 showing infolding of cpithelium in hyperplastic follicle. (Hematoxylin-cosin, x 150.) ‘that the bone dose in the case of the Marshallese children was too small to account