woe . ‘ Volume 66, No. 6 June 1967 + Sa s en LATE EFFECTS OF RADIOACTIVE: IODINE IN.‘FALLO ny . consistency, movable, and nontender. We te . ad es i oo. bee : ats ‘i Scant ho " * Lag Re Hide eget me “ee A -* . ~ ' - fo did not detect general glandular enlargement in most cases. Figure 10 shows one of these glands at surgery, indicating the nature of the nodules. Alchough some clin1cians have doubted that we could palpate 2- to 3-mm nodules, our clinical estimate of these tiny nodules was substantiated at surgery. All subjects except adults (one with cancer) were found to have adenomatous goiter. Figure 11 shows a typical muicro- scopic picture of a nodule with the bizarre characteristics of various size follicles, some of which were cystic and filled with colloid, others hemorrhagic, others microfollicular, others macrofollicular, and some with hyperplasia with infolding of the epithelium. This hyperplasia is demonstrated in Figure 12. Sections of these nodules have been FIGURE 10. Surgical ‘exposiire of thyroid showing ~ = 3 °° nodules (Case 77). studied by a number of pathologists, and ation effects histologically. Figure 13 shows ficiency goiter. has been remarked upon. noma of the thyroid with blood vessel invasion found in a 41-year-old exposed a resemblance to the pattern of iodine deMost claim that they cannot see actual radi- the mixed follicular and papillary carciwasn “4 dat | wot Ficure. }1. Microscopic section of benign adenomatous nodule showing bizarre nature of follicles, some cystic, some microfollicular, some macrofollicular, and some hyperplastic. toxylin-eosin, x 16.) (Hema-