“KON Biopsies of three piamernted lesions SOpe taken from 2 of the wi te \inerieans of tie Rongerik group. Gils ot Soshowed evden: of damage, which ws -leht vee cor tined te tt epidermis, ayer tions of skin at this time revealed same changes persisting in the epidermis ane te a lesser ex tent in the dermis Plites ™ ond ayy Epidermis. The follow ng changes were found to varying degrees focal atrophy of the stratum granulosuri, -ligh! focal pigments disturbances in cells of the basal layer: slight te moderate hyperkerutinization . ind slight dis turbances in polaris foepithedal cells in the still persistent basel papullury proyections In the vermis telanygiectasis super ticially persisted from a -lght 0 moderate de gree in most of the sections, ind contributed the only abnormality noted 3.33 33 eourred ipone of the Americans, characterized » joose far upon combing but without areas Oo Pionec ta Regrowth of hat all individuals com- rence some time during the third month after Lhird series—Oth mone’ past ea posire, Dermis, Pra TION LESION Epilation and Nail Pigmentation Fpitation. The iperdenve ind time of appear ance of epilation in the various groups 1s illus trated in Tables 3. and 3.4, und Figure 3.1 Epilation was first observed of the fourteentt. post-exposure day ii the Rongelap group. wna somewhatlater in tie other groups. fy wast aspotty nature and was confined almost entirely to the head regior. Epilation Was divided arbitrarily into 3 legrees of sever'ty * + indicated loss of hate withou! obsions thinning “a+ indicated Joss of bau sutticrent te cn use thin spots: and “89+ isdieated sar extensive epilation with bald spots Table 1 iHustrates evposure (ft the 6 months’ examination com- Hete regrowth of hairy normal in color, texture, iad abundance had taken place. Plates 13-15, os aad 19 show epilation and regrowth of i} Sal Puqientation. An unusual observation Sis tae appearance of a bhush-brown promentamaf the fingernails which was first well documented on the 23rd post-exposure diy. Phe «issetoration began in the semilunar area of the tt gernasds to « lesser extent in the toenails), ard ~pread OVEN ard sometimes 1 streaks. As the discolored area grew distally the semilunar aren ustutlly became clear, Plate 20 shows pigmented bands 11 the nails at 77 days. At Six Hhomtos, plementation had grown out with the nails. and was no longer evident except in three cases which still showed pigment at the tistal end of the nail. The prgment was on the ancler side of the nail plate. Discoloration of the niatls was seen in a large proportion of tetova higher exposure groups (Tables 3.1 and i Vhe phenomenon appeared to be a radia- Fete response peculiar to the dark-skinned races Soee twas seen mall of the exposed Aimerican Negroes ine none of the white Americans supbese ly recelving the ‘same exposure. This iedon was not observed .n the Utirik people or 4 unexposed Marshallese. Since the nail pigmentation oceurred in individuals without skin ledons, appeared to be the result of a more Penetrating gamma component of radiation. that there was a wreater iegree of epilation it the children +0 to 1) vears) 34 owredi over GO) per cent developing ep:lation to some degree as compared to only vx perrent ou the older ige group. The preponderar-e of -calp lesions i the areas of epilation ondiented that raciatio from the fallout materia or the ski was or marily responsible for the ep iat om, Only trree cases of mild ep latio: teveloped in the Ailinginae children aia Hest ermible ebrbat an tae Verarsesr Therapy Or ‘acweds von-specific. the skin lestons was Most of the superficial heqons were treated with calamine lotion with neooercent phenol, which im most cases reeve the itehing and burning. A few of the syperpigmented Jesions not relieved by ealahae oS ty phenol were treated with pontocaine