"ew 71 CLINSCAL OGBERVATIONS AND TREATMENT Tebte 2.2—URi aad Change ia Greeulecyes io Groups | and I gts with prominent lymphoid follicles, fever of 99-100° F. during the first day. and a purulent nasal and trachea] discharge for about 10 days. It was of interest to determine whether Nesom or Iwas- the appearance of URI could be correlated with the dose of radiation received or with changes in the leukocyte count. _e URI; rise in granulocyteen, =... | URI, ne rise in granulocytes.....____. No URI]; rise in granulocytes....._ ._ . Fifty-eight percent of the individuals in Group I and 56 percent of the individuals in Group IT developed URI. Seventy percent of No URI; no rise in granulocytes... .. | y i6 19 the affected individuals developed symptoms between the 27th and 32nd post-exposure dsys, and the others developed symptoms in the subsequent 2 weeks. Fifty-seven percent of the affected individuals were observed to have an upward trend in their leukocyte counts, the increase being due primarily to granulocytes. Since an increase in the mean granulocyte severity of respiratory infections. The incidence and severity of respiratory infection in Group FV, which had received only slight radiation, was the same as that in Group I and IT. The appearance of URI, therefore, did not ap- pear to be related to the dose of radiation or to changes in leukocyte level. count of the entire population occurred about the 20th postexposure day, it seemed pertinent to determine whether in individual instances the increase was related to the presence of 2.5 Groups I and II With Those in Group respiratory infection. The relationship between the observed leukocyte increase and the presence or absence of IV Tue Diseases THat were seen during the period of observation of Group I and II, which were exposedi to the highest doves of radiation, are listed in Table 2.3. None of the disenses appeared to be related to the effects of irradiation, either directly or as a result of hematologic div upper respiratory symptoms in Groups I and IT is shown in Table 2.2. Seven of the 27 individuals that developed both URI and a leuko- cyte increase developed the leukocyte increase 3 or more days before symptoms of URI ap- peared. It is also of interest that the medical SEoem er AENPE Comparison of Diseases Seen in turbances. personne! involved in the care and study of the radiated individuals had an equal incidence and For comparison. the diseases that were seen during the period of observation of Group [V. which received the lowest dose of Tabie 2.3—Diseases That Were Observed in Groupe I and Il Dmgsse — Neweca | oF isp| - viptals Furuncle . 2 Cholecyatitu. Tinea Gum Abscess Mitteleechmersn Generalised urticana Erythema multiforme Moaraiue beedache - Dweass || | Nreaee ov Inne 1 vepvals oF Bronchitis I 1 i Spondylolistheas impetigo i 5 1 Upper respiratory infections i 1 l i Aphthous ulcet of tongue. Tooth extractions (jeatroentert Foleular tonsallite 1 2 10 47 l

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