several extra days and thought that the blesding was more then wanl but not <alirient to
Tebie 2.1—Pasisem Tresed With Aatibiotio
meaer
i
23
Came
we
| 360 wR
Dave
pe eee
URI and broashitis
with high senuper-
t
URI, severe, with
phacyngitie and
3
ature.
| Penicillin
!
|
Penicillin
}
2
Feniciifia
Peniciliia
3
Penict}lin
8
Rapid progressing
3
®
Traumatic
af fant.
7
Penicillin
S|
Gantrasin
1
- Penicillin
|
12
undermining im-
Cystitis,
=.
2.33
Hemecsecrit Changes
In radiation injury an anemia can be proiluced by three phenomena: a. Partial or complete suppression of erythropoiesis: b. Hem-
orrhage: c. Hemolyaim. (9). The existence of
high temperature.
4,6 Tuct® extraction....
é
Deep extensive
slough of epidermis of foot.
7
« Iafleamed tonsils
with high temperature and URI.
te
cause them concern.
—
|
Furuncle on buttock |
Furuncle on fore
head.
2?
|
Penicillin
Peniciilin
te
deacribed in detail above. Each appeared to
have evidence of a bacterial component associated with URI and antibiotics would have been
indicated had they not been irradiated.
All
other individuals were not neutropenic at the
time of treatment and were given antibiotics
for specific mdications. There was no instance
in which it wax considered necessary to give
the latter is not universally accepted as a characteristic part of radiation injury. Since hemorrhagic phenomena were not observed a severe
anemia would have been expected only if
erythropoiesis were suppressed severely for a
long time. With complete suppression of
erythropoiesis and an unchanged life span of
the red cell one would expect a deficit of 0.88
percent per day since the human red blood celt
has a life span of approximately 120 days.
Nineteen individuals in Groups I and IT hed
hematocrits between 31 and 35 percent. Nine
of the 19 were children, aged 1 to 5 years and
would be expected to have a lower hematocrit
than normal adults: four were over 7) years of
age, in which age group a decreased hematocrit
is frequently present without obvious cause.
Two of the 19 had had menorrhagia prior to the
determination, two were 3 to 4 months preg-
nant and had not received supplementary iron,
and two were young women. These hematocrits could be ascribed to physiological variations rather than to the effects of irradiation
prophylactic antibiotics for neutropenia per ae.
on hematopoiesis. Supplementary iron was the
only therapy used for the mild anemias ob
2.32
erythropoietic suppression was observed even in
Clinical Observations and Piacelet Counts
All individuals with a platelet count of
100,000 or less were examined daily for evidence
of hemorrhage into the sktu, mucous mem-
branes and retinae. Urine was examined daily
for red cells and albumin, and women were
questioned concerning excessive menstruation.
There was no evidence of any hemorrhage even
though $1 individuals reached platelet levels
between 35,000 and 65,000, Two women menmtruated when their platelet counts were 154),000
and 1M) respectively. Hoth menstruated
served. Thus no definite evidence of prolonged
individuals who had received 175 ¢ whole body
radiation.
2.4 An Epidemic of Upper Respiratory Infection Occurring During the
4th and 5th Post-Exposure Weeks
Berween Tee 2th amd the 42nd post-exposure days an epidenue of upper respiratory
dispane (URE) occurred. The respiratory in-
fection consisted of maderate malaise, pharyn-
ds
govecTs oF leCTING RADIATION
2