AQQT 15 19 Aprit 1955 (Consuctant Covuenty © Neuropatiorocy) AFIP Noe 259900 1. FSve eLocks OF GRAIN .IN THE CASE REFERRED TO ASOVE WERE SUBMITTED FOR EXAMINATIONe CNTENTATION OF THESE BLOCKS IN IN@ DICATED IN THE SKETCH WHICH ACCOMPANIED THE BLOCKSe 2. THE STAINGNG WETHODS EvPLOYED werne H & Ey 3. Spock Conzapnins Hypotisnanus ayo Basa Mucrets Ricnre van Gicson, Lacere (uvertn), Sonoran (neave FIBERS). : ee ar ee HISTOLOGICAL EXAMENATICN OF THE MENINGES REVEALS WILD ARTERIOLOS SCLERIISe TWH & E STAINED SECTIONS OCCASIONAL CELLS LYINS FREE IN THE MONENGES COHTAPNED DARK BROWN PIGKENTe In THE CEREBRAL con@ TEX ALD BASAL KNUCLED, SOE OF THE NERVE CZLLS SHOW SLIGHT LIPCe FUSCIN PIGMENTATION CHARACTERISED INH & E STAINED SECTIONS BY THE nee . NON-CCRP | oT Fe ee . a" . PRESENCE OF PALE BROWN GRANULESe 7 ‘ f a ee CRESYL VIOLET, HEN STAINED BY GRESYL VIOLET, THE GRANULES TAKE A BLUE@GREEN TINGEe BLUEGREEN DROPLETS ARE FOUND ALSO IN THE CYTOPLASM OF GLIAe OLIGODENDROGLIA IN THE WHITE VATTER SHOW WARKED HYDROPEC SUCLLINGe THE MYELIN SHEATHS AND AXES CYLIK@ DERS ARE WELL PRESERVEDe IN THE PUTAVEN, CAUDATE KUCLEUS AND GLOSUS PALLIDUS, AND 1H LESS MEASURE JN THE CEREBRAL COATEX, THERE ARE SCATTERED ALZHEIWER GLIAL cetrs (Type 2); THESE CELLS, R=GARDED AS DEGENERATING ASTROGTTES, ARE CHARACTERIZED BY A LARGE G1 ZARRELY@ SHAPED (K|DNEY*BEAN, ETCe) PALE NUCLEUS WITH VERY SPARSE PERINU@ CLEAR CYTOPLASIMs No CHANGES ARE MAy AND NO CYTOPLASMIC PROCESSES. 4, SEEN IN THE HYPOTHALAMUS OR EPENDT@ Precentra, Graus atip Supeapor FrRontat Gyrus, Lerr (2 SECTIONS) § NOTED IN THESE SECTIONS ARE MILD MENINGEAL ARTERIOLOSCLEROSIS, SLICHT LIPOFUSCIN PISIENTATION OF NERVE CELLS, OCCASIONAL CHRCVAS TOLYStS, AND SULEL GROUPS OF PYKNOTIC SHRUNKEN NERVE CELLSs Lavinae THON OF CORTICAL NERVE CELLS 18 DISTINGY AND A FEW SCATTERED ALZHEINER GCLRAL ceLELS (Type 2) ARE SEEN. CRESYL VIOLET STAIN REVEALS SHALL ELUE@GRIEN DROPLETS §N GLIAy ESPECEALLY IN THE ASTROCYTES OF THE CORTEXe IN THE WHITE VATTER THERE $8 BARKED RKYDROPIC SWELLING OF OLIGODENDROGLIAe THE KYELIN SHEATHS APD AXIS CYLYNDERS ARSE SELL PRESERVED. _. _US DOE ARCHIVES | 820 US ATOMIC ENEKGY "_.___COMMISSiON , BEST COPY AVAILABLE