Volume 66, No. 6 June 1967 LATE EFFECTS OF RADIOACTIVE IODINE IN FALLOUT 1227 consistency, movable, and nontender. We did not detect general glandular enlargement in most cases. Figure 10 shows one of these glands at surgery, indicating the nature of the nodules. Although someclini- cians have doubted that we could palpate 2- to 3-mm nodules, our clinical estimate of these tiny nodules was substantiated at sur- gery. All subjects except adults (one with cancer) were found to have adenomatous goiter. Figure 1] shows a typical microscopic picture of a nodule with the bizarre characteristics of varioussize follicles, some of which were cystic and filled with colloid, others hemorrhagic, others microfollicular, 12. Sections of these nodules have been studied by a number of pathologists, and a resemblance to the pattern of iodine deficiency goiter has been remarked upon. Most claim that they cannotsee actual radi- Ficure 10. Surgical exposure of thyroid showing nodules (Case 17). ation effects histologically. Figure 13 shows the mixed follicular and papillary carci- noma of the thyroid with blood vessel in- vasion found in a 4l-year-old exposed Ficure 11. Microscopic section of benign adenomatous nodule showing bizarre nature of follicles, some cystic, some microfollicular, some macrofollicular, and some hyperplastic. (Hema- toxylin-eosin, x 16.) Peteineanettiqe others macrofollicular, and some with hyperplasia with infolding of the epithelium. This hyperplasia is demonstrated in Figure