oO 2 st 7 I 16 1 48 22 4 = a S s 3 ne 5 suse & — ae eee a -™ a 7o 78.9 3¢ 6 coo Rongelap people of the Utirik and Rongelap comparison populations. These latter cases were in people over 50 years of age, whereas in the Rongelap exposed adults, the nodules occurred before the age of 50 years. In view of the seriousness of this development, the highest exposure group on Rongelap was started on thyroid hormone therapy in order to protect the glands against further thyroid-stimulating hormone (TSH)stimulation and hopefully to reducd the possibility of further development of nodules as well as to cause regression of + os . ‘ existing nodules. Accordingly, in September of 1965 daily treatment was begun with synthetic thyroxine, 0.3 mg to those under 50 years of age and 0.2 mg to those over 50 "oS o years * Surgery has been performed on 11 subjects. Three were taken to Guam in 1964, where thyroidectomy was carried out at the . 3 3 3 2's ge 4 ried out a numberof thyroid studies before surgery was done in Boston. These studies included iodine uptake, serum TSH level, f E 3 serum thyroxine level. Thyroglobulin anti- © seen. Dr. Robbins will speak further about P Be haven National Laboratory where we car- @=-3 00 wn * body tests were made, but no increase was 2 ~% 54 these studies. Subtotal thyroidectomy was J {3 s & |8% na = © = several nodules have been detected in older taken back to the United States to Brook- By 7 = represents 12.5%. It should be noted that 24thyroid scan, basal metabolic rate, PBI, and et ee c Ailinginae group there was 1 case that E lo me g us = ‘> y 10 years, there have been 3 adults with thyroid nodules (5.5%). In the smaller “$2 Naval Hospital. Eight other cases were oo Z among those exposed at an age greater than 5 2 % 288 o &&&2 o o © I 700-1 ,400 12 ~ o » rads 9 2 oss 19 Dose* Thyroid Group I 350-600 rads Group Dose* Thyroid % 14 1 54 rads I 160 y 175 % 14.3 co“ 0.0 Dose* Group Thyroid Abnormalities Estimated No. in Abnormalities Estimated No. in a y 69 Group % 0.0 10 Abnormalities Abnormalities in No. - No. in Estimated so = Island Group Age (1954) 20-40 years Age (1954) >40 yearst Age (1954) 10-19 years Age (1954) <10 years Thyroid Abnormalities (Nodules and Hypothyroidism )-—Marshallese Populations Examined 1964 Through 1966 TABLE 4. malities have been noted. On Rongelap, } In estimating the thyroid doses to the Ailinginae and Utirik exposed groupsit was assumedthat such doses were proportional to the thyroid doses of the % *~ Annals of Internal Medicine same age range, again no thyroid abnor«os Ww 30.9 S 55 Abnormalities No. _ Som — All Ages i Ny No NATIONAL INSTITUTES OF HEALTH CLINICAL STAFF . « = carried out in Boston by Dr. Bentley Col- 22a cock. Total. thyroidectomy was carried out * : 8% on the patient who showed a mixed papil{9-284 lary andfollicular carcinoma of the thyroid. Sa /e 60'S vo B.5 a £8 & Clinically these nodules have appeared in . = some cases to be single nodules, but at sur- s Pls a gery they were nearly all found to be multi- @ nodular. They were usually soft to firm in