1228 NATIONAL INSTITUTES OF HEALTH CLINICAL STAFF Internal Aon,of woman. There was also localized metastasis into a lymph node. Subsequent studies after complete ablation of her thyroid gland have revealed no indication of metastases. The earlier cases of thyroid abnormalities have been previously described (10, 13). I would like now to say a few words about thyroid abnormalities as related to growth retardation in the children. As I indicated earlier, we had long been puzzled as to why these children had showna slight degree of retardation in growth. We knew that the Japanese children had been reported to have someslight retardation, par- ticularly the male Japanese children at Hiroshima, but that picture was confused by such factors as physical and psychic trauma and nutritional deficiencies. We felt, oo. FicurE 12. Microscopic section of nodule in Figure 7 showing infolding of epithelium in hyper- plastic follicle. (Hematoxylin-eosin, x 150.) that the bone dose in the case of the Mar-t 3 . shallese children was too smal! to account} for any direct effect on epiphyseal growth. Ficure 13. Section showing invasion by metastatic papillary and follicular carcinoma of the thyroid into blood vessel (Case 6#). (Elastic, x 100.)