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low excretors either heterozygous or homozygous
for the dominant allele. Striking differencesin the
incidence of high excretors in various populations

have been demonstrated, and it appears thatthis

genetic polymorphism may be of considerable
value in anthropo-genetic investigations.??:??
As a part of the study of the genetic relationships and origins of various Pacific peoples, this report extends observations on BAIB excretion to
the Micronesians inhabiting the Marshall Islands.
The fact that some of the Micronesians were exposéd to considerable radiation in 1954 is of
special] interest here, since it is known that radiation exposure can, temporarilyat least, increase

BAIB excretion,”® and studies on the Marshallese

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population may elucidate possible long-term effects.
Urine samples from 65 exposed and 119 unexposed people (75.7% of the population ofthevilJage) were collected in plastic bottles containing
thymolpreservative. The sexes were equally represented, and the ages varied from 3 to >70 years.
In somecases several members of the same family

were included, and some kinships suitable for

genetic analysis were available. Eighteen samples
collected on Utirik were also studied. Urines were
kept at 4°C and shippedin refrigerated containers
to Seattle for analysis. These studies were carried
out by one of us (B.S. Blumberg) and Dr. S.A.
Gartler of the Department of Medicine, School of
Medicine, University of Washington. Studies were

completed 2 to 3 weeks after collection of the spec-

imens. Determinations of BAIB were carried out
by high voltage electrophoresis on paper,?* and
creatinine was determined by the alkaline picrate
method.
Radionuclide Body Burden Evaluation

The methods used in the radionuclide body
burden evaluation are described later in a separate section.

carried out every year need be done only once
every two to three years. In addition, as pointed
out before, the Trust Territoryofficials were concerned about the slowness of economic recovery of
the Rongelapese andfelt that the numerousvisiting scientific teams, particularly those with large
ships and crews, were partly responsible for the
unrest of the people and therefore requested that
the size of the surveys be kept to a minimum, It
was decided to defer the gamma spectrographic
analysis until 1961. The Trust Territory officials
agreed to greater participation of their medical
personnelin future surveys and to the use of one
of their cargo ships (Figure 9), which routinely
made the roundsofthe islands for gathering copra, for carrying out the survey at Rongelap. Accordingly, for the 1960 survey the team consisted
of only one physician and one technician from
Brookhaven National Laboratory, and the remainderof the medical group, arranged bythe
Trust Territory, included its Director of Public
Health, two Marshallese medicalofficers, and two

Micronesian laboratory technicians. The Director
of Dental Services and one of his dental officers
also accompanied the team to carryout treatment
of the people. The District Administrator of the
Marshall Islands accompanied the team in order
to consult with the people on their agricultural
program. *
As in the previous year, several of the exposed
people nowliving at Kwajalein and Majuro Atolls
were examinedattheseatolls prior to the Rongelap visit.

DOE ARC
HIVE

S

PROCEDURES

As in previous surveys, examinations were
carried out in the dispensary and the schoolhouse
in Rongelap village. Interval medical histories and
complete physical examinations were carried out
*Again in 1960, when the team arrived at Rongelap, the mag-

1960 Survey
BACKGROUND MATERIAL

The 1960 survey was reduced in size and scope
and |imited to a very brief examination ofthe ex-

posed people only. Several factors brought about

this change. The people had recovered to the extent that certain special examinations previously

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istrate requested a mecting with the people. Theline of questions
and discussion was about the same as that reported for the previous year. Resistance toward the examinations was expressed by
only one or two of the people. Objections were again raised
against the ban on eating coconut crabs, which selectively concentrate Sr** to such an extent that their consumption hadto be

prohibited (Figure 4). The people were assured that these crabs

were being repeatedly examined and that, when it was safe to

eat them, immediate noufication would be given. Fish poisoning

apparently had been less ofa problem during the past year since
only one case had been noted, and the subjeet was not brought
up again. Following this meeting, cooperation bythe people in
the examinations was almost complete.

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