ee:

38

phosphatase staining of neutrophils showed a generally normaldistribution of positive cells, as in
the previous year. Basophil counts of 4000 cells
showed noincrease in levels above the norma!percentage in any subjects, either exposed or unexposed, in the 1959 and 1960 surveys, exceptfor
one 6-year-old exposed boy ( #3).* The mean
percent basophil count (counting 4000 white cells)
for the exposed Rongelap group was 0.42% in
1959 and 0.93% in 1960; in the Ailingnae group,

0.29% in 1959 and 0.80% in 1960. Basophil counts
on the unexposed group are not yet complete for
1959. The individual values for alkaline phos-

phatase and basophil counts are presented in
Appendix 5.
Complement Fixation Tests

Theresults of the complementfixationtests are
shown in Table 23. In discussing these results Dr.
R. J. Heubner madethe following comments:
“IT suppose the most interesting thing is that

there is evidenceof infection with almost all the
groupsofviruses that wetested for. It is important
to point out that complement-fixing antibodies are
generally less persistent than are hemagglutina-

tion inhibition,and neutralizing antibodies. Therefore, the high levels of adenovirus and HA | complement-fixing antibodiesreflect either recentin-

fection or multiple infections with various members of the parainfluenza family of viruses. The
low levels obtained for other agents, such as influenza A, influenza B, HA 2, CA, mumps, LGV,

and Q fever mayreflect low levels of infection with
these agents, but morelikely might reflect the fact
that such agents have not been prevalentin recent
years. Thus, one might conclude from the data
that the Asian influenzavirus has not yet seriously

involved the Marshall Island populations,orelse,

of course, that the complement-fixing antibody
produced bythe Asian influenza has notpersisted.
“T would rather suspect from the age distribution that Asian influenzastill has not reached
these people, and that one might look forwardto
see if they are involved at some future date. Similarly, the age distribution of influenza B antibodies suggests that it has not occurredfor atleast
6 to 10 years. The absence of HA 2 antibodies suggests that the virus has not been prevalentin re*In 1959 his basophil count was 2.1%, WBC 8600, and alka-

line phosphatase negative ceils 79%. In 1960 his basophil count
was 3%, WBC 6100, and alkaline phosphatase negativeceils
70%. No abnormalforms were seen.

cent years. However, the total absenceof anti-

bodies even in persons over 40 suggests the possibility that it has not occurredin this population
at all, but the first interpretation is equally good.
The same comments would refer to the CA virus
or parainfluenza 2, but here the more likely interpretation is that the virus has not been presentin
the recent past, but the presence of antibodies may
suggest that it had been present 16 or more years
earlier. Since there is some overlap in antigens and
antibodies between mumpsandthe parainfluenza
group, the CA reactions and/or the mumpsreactions could conceivably merely reflect infections

with other members of the parainfluenza group.
“It would be interesting to find out to whatextent the psittacosis group and fever represent a
threat to this population, and of course in the
birds and domestic animals as well.”
Dr. Heubner’sforecast of Asian influenza in the
Marshall Islands from the Rongelap data is interesting in that an epidemic of serious proportions
did occur at Kwajalein Atoll in January 1960 re-.
sulting in significant mortality.
The average antibodytiters for the different age
groups in the exposed people were, in nearlyall
cases, lower than in the corresponding unexposed
age groups. It 1s not known whetherthisis a significant findine: further studies will be done to
determine this. .\t three vears after exposure, the
primary response to tetanus antitoxin averaged
slightly less in the exposed people than in the unexposed.” However, because of the smal! numbers
of people studied, this finding could not be considered significant.

Sodium and Potassium Leveis, 1959

Potassium intake appeared to approximatethat of

Americans, namely, =40 to 100 mEq/day. Salt

intake varied widely as judged by urine excretion,
ranging from 2 to 18 g/day. Therelatively high
salt consumption of some individuals is undoubtedly related to the irregular consumption of

canned C rations, to which 2% NaCl is added

routinely during preparation. The medianintake
of salt appeared to approximate that of male employees at Brookhaven National Laboratory,
namely, ~10 g/day. This undoubtedly represents
an increase over the intake in earlier years when
only native foods were eaten.It will be of interest
to note whetherthe incidence of hypertension also
will begin to increase. At present the prevalence
of hypertension (B.P. greater than 140/90)is 9.2%

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