7.

Granulocyte transfusions would be des

v

in patiencs with a sranulocyte count talling ‘elow 20¢,.1
these are uot practical om any
6.

Infection

is

large scale.

the vreatest threat to

sisuiticant fever greater than 38°C should aru: 3G
infection

in

tne granulopenic patient.

bacterial

infection,

or

Teaver

fever sustained wore

Strong suspici.a of

sitn
tran

is an inuirteticon

thougn cultures ar<

the most likely azent is an wr-anism tram norte. iseel

Lnitial therapy shouid include aminoglvycosite ane caurbdenicillic wits

additional antibiotics baing adced as

sensitivities

‘tf cultures 2zre negative sor f

therapy with a combination of trinep ou

rises above

S5GuU/i1,

fever subsides, ana evidence of

Washed pacxed

Iinicction

red blood cells shouls «2 given 23

ct

tre

0
is

ve continuea until

ct

ict snould

tt

therapy,

After initiaticr ct bLrozcesueltr
fa

amtibiotic

considered.

re

a

or with ampho ericin may be

9,

bacteriul

°
n
‘¢

persists,

that are obtained.

ingicatec by
a

cn
4
ef
2
c

flora,

Since

si ls of

14 ho.rs

for initiating systemic antibacterial therapy even
negative.

tlivical

di

isuicutes

tc

west

the Aemoglobia above 3.5 5.
10.

ALL

infusicn

bioog

into

oroducts

shoule be

frradiatea with

tne patient in order to kill

250 rac

le*ore

lyv-,uocytes that

pruliterate anc inpairc tne possiuility3; of a tuze farrow transpla nt.
Li.

one

racraw

transolantatior «ih

sol:

cicely

.:

inticn..c:

tak

irradiation casugity because uncertaluty about tice magnituce of toe
radiation do3e,

inhomogeneity of

tne dose, and the

aqose de within the limits of rescue of bone carruw
approximately €90-20509 rad.
suppless2aq ana
no

therapy.

twin

transfusion of

is

the lynuphocytes

Above rougniy 24!

collected pronptly,

te casuali sill
A zenetical-.-

che ideal donor.

Sone marrow tron his twin.

above as an Ladgicaticn for
from’ the earlier discussiun
Anusen with any cegres of

aAltnouzh radiztion douse was

bone marrow transple.itation, it is
tiat doses art

certal mty anc

expercicental conditions where

usec

to te netea

the depth-dos- curves are nt

the dous]e5 used 4oive #ere ase lt

on

radiation was delivered in a meuner ts cise

uniforn whole tocy distribution of ahsurbea enerzy.
ls

50GTu4 I

tne¢

tranizlantatias

nave teen HLA-typea and donors will nave been icentifiec.
icentical

that

Below 560 rac inreunity is nor st

transplants are rejected,

Fron

requirement

Select target paragraph3