7.
Granulocyte transfusions would be des
v
in patiencs with a sranulocyte count talling ‘elow 20¢,.1
these are uot practical om any
6.
Infection
is
large scale.
the vreatest threat to
sisuiticant fever greater than 38°C should aru: 3G
infection
in
tne granulopenic patient.
bacterial
infection,
or
Teaver
fever sustained wore
Strong suspici.a of
sitn
tran
is an inuirteticon
thougn cultures ar<
the most likely azent is an wr-anism tram norte. iseel
Lnitial therapy shouid include aminoglvycosite ane caurbdenicillic wits
additional antibiotics baing adced as
sensitivities
‘tf cultures 2zre negative sor f
therapy with a combination of trinep ou
rises above
S5GuU/i1,
fever subsides, ana evidence of
Washed pacxed
Iinicction
red blood cells shouls «2 given 23
ct
tre
0
is
ve continuea until
ct
ict snould
tt
therapy,
After initiaticr ct bLrozcesueltr
fa
amtibiotic
considered.
re
a
or with ampho ericin may be
9,
bacteriul
°
n
‘¢
persists,
that are obtained.
ingicatec by
a
cn
4
ef
2
c
flora,
Since
si ls of
14 ho.rs
for initiating systemic antibacterial therapy even
negative.
tlivical
di
isuicutes
tc
west
the Aemoglobia above 3.5 5.
10.
ALL
infusicn
bioog
into
oroducts
shoule be
frradiatea with
tne patient in order to kill
250 rac
le*ore
lyv-,uocytes that
pruliterate anc inpairc tne possiuility3; of a tuze farrow transpla nt.
Li.
one
racraw
transolantatior «ih
sol:
cicely
.:
inticn..c:
tak
irradiation casugity because uncertaluty about tice magnituce of toe
radiation do3e,
inhomogeneity of
tne dose, and the
aqose de within the limits of rescue of bone carruw
approximately €90-20509 rad.
suppless2aq ana
no
therapy.
twin
transfusion of
is
the lynuphocytes
Above rougniy 24!
collected pronptly,
te casuali sill
A zenetical-.-
che ideal donor.
Sone marrow tron his twin.
above as an Ladgicaticn for
from’ the earlier discussiun
Anusen with any cegres of
aAltnouzh radiztion douse was
bone marrow transple.itation, it is
tiat doses art
certal mty anc
expercicental conditions where
usec
to te netea
the depth-dos- curves are nt
the dous]e5 used 4oive #ere ase lt
on
radiation was delivered in a meuner ts cise
uniforn whole tocy distribution of ahsurbea enerzy.
ls
50GTu4 I
tne¢
tranizlantatias
nave teen HLA-typea and donors will nave been icentifiec.
icentical
that
Below 560 rac inreunity is nor st
transplants are rejected,
Fron
requirement