oe ae ~pt
TR
eS
F

Geuth was ascribed

ss

‘The curve

The next

snowed infection and hemorthage as causes of
the granulocyte count hag a

least decline in

the

showing

the granulocyte count with a mortality of

in

The animals at autopsy

Geath.

aaa Eee ee

to intection and cumplicated by henerrhage.

curve shows a slower decline
aC%.

ph.

e

muttality of 10% with hemorrhage and infection
In Figures 3 anc 4,

the critical

role‘of

the causes of death.
the ,ranulocyte count in

Japanese ag a oeterminant of mortality is illustrated.

the

i

Figure 3 plots the

q

‘

mortality against the blood counts observed in the third, fourth, and fifth
weeks.

fron
"orem 1

The

lower

the white count

the higher

the sortality.

Figure 4

“

t

cortelates the mortality at the end of nine weeks with the lowest white
The most clearcut cotrelation of

count observed,

the

infection is in the work of Miller et al. (26), shown in Figure &.
figure,

there

is a clearcut correlation of mortality with

animals having positive
studies

in hussia

and

p:

importance of

In thig 2

gr

the

fraction of

4

wh

blood and splenic bacterial cultures.

Subsequent

¥

ex

of

ex,

the L.S,

extena and confirm

the

rele

of

infection,

Liluwanian and Izvekova (30) have studied a whole series of antibiotics and fa
thezr use

in the

treatment

of radiation injury

a

They administered kanamycin,

i

oxacillin,

:

by mouth for a

as

a

!

ana

wletetrine,

Une antibiotics

rats, ane rabbits, * 2

tetracycline,
were

rays.

(33

ampicillin,

administered

total of 20-25 days starting 24 hours after

lethal dose of gamma

effective

erythromycin,

in wice,

twice

fal
a day “J:

exp-

irradiation withs :

fron

A coubination of antibivtics Was nore

than single antibiotics.
erythromycin, or

such

The combination of kanalInycin with

is ]

.

tettacycline o1

tetracycline with ampicillin was most wx|

;

effective.

f
,

more than 50% survival. _ Chernov et al. (31) and Trushina et al. (32) Sige
administered nexamine prior to exposure of dogs and nonkeys followed by.

50% pb
ceome

administration of antibiotics.

exper:

The antibietic combinations changed a near

streptomycin were

used.

100% mortality, ‘te

For ,

In the case of dogs, penicillin and

The survivals

increased from 11% to 69%.

studies on monkeys, a combination of kanamycin,

and penicillin was used,

X-re.

oletettrine,

:

phante

streptomyed

4

There was an increase in survival from 20% ta

y.

SP the

5G% «
The Effects of Geometry of Exposure and kadiation Injury on
Lepth-Lose

The

Curves

and

inadequacies of

be illustrated by showing

biolugical

Lffectiveness

using an air douse of
the

¥

7

radiation for prognosi@RE -

influence of exposure peonetry and enet

: . the
°

the

Bense

ae 7 gathe

t

ing

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