SUMMARY SHEET Committee on Radiation Studies(MAIL BALLOT) H-1496(C) February 1954 Council Meeting Henry G. Kupfer, M.D., Professor of Clinical Pathology and Director of Laboratories Medicel College of Virginia, Richmond 19, Virginia "An Investigation of Certain Tissue Protein Changes in Irradicted Aninals" Recommended Reguested Yeor Previous Commitment Gront Period $13,601 2nd(C) RECOMMENDATION: Approval ~ 5 Disapproval - 2 No vote FRIORITY SCORE: -4 300 COMMENTS : Appr oval The progress report indicates an adequate amount of work and sonic progress, although no conclusions, Ccrtain statenents made in both the application and report are highly uncritical and show considerable un- faniliority with the known effect of whole body irradiation on tissue fragility, The statistical evaluation is misleading, More aninals and repeated experiments are needed to evaluate the significance of the small difforences involved. The sum requested for additional personnel and for animals seens excessive; likewise the sum for travel, ‘pprovel is recommended, largely because of the necd for checking the elcetrophoretic data obtained, using other tissues and other species, but in reduced amount, ares $2, 7443. $3, 5003 and 35, 000. The sums suggested (over ) \ FINAL ACTION: February 1954 Qa. ; MS cuccort; This rojeets Teah We Renested eLL96 f —~) A 2#4 4aALoe $2,7d Granted 2257hly Grant eriod WY53 = 3/3Y5h