12 Hematolo T, KUMATORI order of 350R to 4 and LALANNE, C. M., Kimura, K., Ikepa, N., Kimura, K., Kawanisut, H. and Kimura, M. (1956): ibid. logie, 6, 561, (1963) I, 521. Koyama, Y., KuMaTori, T. et al. (1955): Iryo, 9, 1. Tonizing Radiation« Kumatoni, T. and Mryosui, K. (1963): Diagnosis and Treatment of Radioactive . Poisoning, 253, International Atomic Energy Agency, Vienna. ietic tissue, Int. A (1967)). We have compare the curves of Yu ‘ Kumatori, T., IsHtnana, T:, UEDA, T. and Mryosui, K. (1965): Medical Survey o Japanese Exposed to Fallout Radiation in 1954—A Report after 10 Years, National Institute of Radiological Sciences, Chiba. cases, and here ag Mixamo, Y., Mryosut, K., Suimizu, K., IsHikawa, K., Kurryama, S., Koyama, Y. and of Hematology, 1, 29, Pan-Pacific Press, Tokyo. Miyrosui, K. and Kumatori, T. (1964): Nihon Ketsuekigaku Zensho, 3, 660, Maruzen Co., Tokyo. DISCUSSION Concerning most cases. In our cases, we used Duxe’s method. The bleeding timeis damage, andits relationship to exter- severe cases the bleeding time at the Dr. Kumatori (Japan) : Sincethis fatal case was anemic and revealed bone marrow aplasia, he received blood minutes. I think this came back to normal at about 10 weeks or so after transfusions. Therefore, serum hepa- titis can’t be ignored. However, at the same time the existence of radiation-induced liver damage should be considered. At present it is difficult to decide the cause of his liver damage. Weshould consider the probability of the radiation-induced liver damage, because in some publications we can see a similar histological picture of the liver of a patient who wasirradi- the exposures, though I have no correct data here. Dr. Sanc: And how about the fib- rinogen concentration? Dr. Kumatori: Fibrinogen concent- ration was almost normal from the beginning of the examination. Dr. Tusiana (France): I would like something about hemorrhagic tendencies on these cases, Would you tell me how long did hemorrhagic tendencies continue after the irradiationP Dr. Kumatoni: In my cases the hemorrhagic tendencies were not so to ask Prof. Kumatorti if he has an idea of how uniform was the dose delivered to your fishermen. I ask you this question because we have a rather large experience of total-body irradiation for mostly kidney transplants in human patients, and there are 2 main differences between your results and the one we have also. The first one is that aplasia of the blood occurs much earlier in our patients, and the rigidity also occurs much earlier. The 2nd one is that the minimum number of leukocytes is ing time was observed in a few cases. You can see normal bleeding time in the order 1 to 200 leukocytes per cubic millimeter, after a dose of the ated therapeutically. Dr. Sanc (Korea): I thank you Dr. Kumatori, I would like to ask you severe. The prolongation of the bleed- “ We. critical stage was as. long as about 10 much smaller in our cases, being of Adilsh apanas’ ts nal or internal radiation exposure? normally 3 minutes, and in 1 or 2 + Dr. Currron (U.S.A.): the one fatality, would you care to comment on the nature of the liver Fest Miyvosut, K. and Kumatont, T. (1955): Acta Haematologica Japonica, 18, 379. - Mryvosui, K. and Kumatonri, T. (1962): Proceedings of 8th International Congress Lat 5 of ja Sd aya te 5 + Bomb Test Explosions,I, 1313, Japan Society for the Promotion of Science, Tokyo. a Kumaton, T. (1956): Research in the Effects and Influences of the Nuclear same difference, 2 tion of these data the difference bets cases and the pt patients was that patients the dose with a maximum ‘ minus 4 per cent, of accidents the u less, and of the o Dr. KuMATORIL: opinion. In my