+ Hematological Effects on Heavily Irradiated Japanese Fishermen cytes of the fishermen, and morphological abnormalities of spermatozoa were also observed. Indications of recovery were observed in somecases after about one year, but mostly first signs* of regeneration did not show earlier than about 2 years after ex- ~ Stable unstable {/} (/}* cells % cells % 0.14 (1/10) 0.14 (1/10) (9/13) (3/13) (14/15) (5/15) 2. 28 3. 45 2. 88 posure, with following production of children. SUMMARY 0.46 The hematological changes of Japanese fishermen exposed to fallout in 1954 were reported with other findings. Generally speaking,it is difficult to estimate correctly the exposed radiation 0.45 0.56 (15/16)NB (6/1) 6) C 1. 20 8/10) 211. dose soon after the accident. 0. 67 findings. From this point, hematological changes are ‘an important information 0.74 BM at er of cases examined. Lae a e observed (Table 2). markably higher th an PO HESAREOe UII ni Bie tr98 0+ BIG ME at stable abnormal ities - tion n... 67 per cent | a per cent 2 observed iin 5 ca ses. a" ‘ies. While st able Otypes of their ow n, aryotypes. fay we Ping extent of the ini tia] onded to the esti mat- — Pe “aean values of st able =, r to the Ph! chromo- Ups according to th e alues of neutrophil s Therefore, treatment of heavily irradiated per- sons should be decided by the daily appraisal of clinical and laboratory (4/10) '++-4 per cent 71 to decide the therapy which should be given to heavily irradiated subjects. As to the Japanese fishermen, it seems to be very important as well as necessary to detect the significance of subtle changes such as they arestill observed in hematological and cytogenetical examinations. REFERENCES Amano, S. (1953): Genshi Bakudan Saigai Chosa Hokokushu. II, 914. Gakujutsu Shinko Kai, Tokyo. Nihon Anprews, G.A., SITTERSON, B.W., Kretcumarn, A.L. and Brucer, M. (1961): Diagnosis and Treatment of Acute Radiation Injury, 27, World Health Organization, Geneva. Cronkite, E.P., Boxp, V.P. and Dunnam, C.H. (ed.) (1956): Some Effects of Ionizing Radiation on Human Beings. U.S. Government Printing Office, Washington, D.C. Guskova, A.K. and Batsocotov, G. D. (1956): Proceedings of the International Conference on Peaceful Uses of Atomic Energy, 11, 35, United Nations, New York. HASTERLIK, R. J. and Maninevul, L. D. (1956): Proceedings of the International Conference on Peaceful Uses of Atomic Energy, 11, 25, United Nations, New York. HEMPELMAN, L.H., Lisco, H. and HOFFMan, J. G. (1952): Annals of Internal Medicine, 36. 279. IsHiHaRA, T. and Kumatonr!, T. (1965): Acta Haematologica Japonica, 28, 291. IsmtHara, T. and Kumators, T. (1967): Human Radiation Cytogenetics, 144, North Holland Publishing Co., Amsterdam. IsuiHara, T. and Kumatori, T. (1969): Japan Journal of Genetics, 44, Suppl. 1, 242. Jammet, H.P. (1961): Diagnosis and Treatment of Acute Radiation Injury, 83, uarities with he ma- zoa is describe d for mum numbers we re wering of mobi lity 2 Sete -~ % oO Peeone “ ag58 Spat re obey tl 45 eS BR aoe mWcon eS World Health Organization, Geneva. Kixucni, T., Waxkisaka, G., Akact, H. and Goto, H. (1954): Bulletin of the Institute for Chemical Research, 4, Kyoto University, Kvoto. Kimura, K., MINaM!, E., Honpa, M. et al. (1956): Research in the Effects and Influences of the Nuclear Bomb Test Explosions, I, 497, Japan Society for the Promotion of Science, Tokyo. oty tae oe *t ea ners . ‘an 7 wil aS . re . rae peak! aw me . me . . Ls aye ke oe te: =,eesuite 5maeod . oo eS BeetSr ITS: saci eA s ise OL