|
|
160|/-
T
|
a
|
140 }—
a
_
4
a
E 130K
~
MEDIAN STATURE
%
4
UNEXPOSED BOYS
a
~
lad
{
ax
a
7
vt
2
a
2
a
-
\
=
a
Sg
7
!
i
Woe
as
¥
100—
4
90L-
j
~Ww
Z
THYROID
|
1
>
—
5 120
a
e
w
|
a
STATURAL GROWTH
SUBJECTS #38 #5
1S0;—-
~i..--L1
28
.
i
:
SKELETAL AGE
3
oO HEIGHT AGE
— SUBJECT NO.3
==
SUBJECTNOS
J
HORMONE
|
=
STARTED
B0r—
4
l
3
_|
6
!
9
1
12
CHRONOLOGICAL AGE (YEARS)
|
15
Z
Figure 31. Relative patterns of statural growth (corre-
lated with chronological age) in the two boys who had
marked hypothyroidism. Comparison is with unexposed.
Note enhanced growth after thyroid treatment.
Figure 33. One of the two boys
(25) showing most retardation
of growth with developmentof
hypothyroidism. Left: near the
beginning of thyroid hormone
treatment(1966, age 13); right:
after 3 years of treatment(1969),
showing remarkable spurt in
growth and development with
dissappearance of hypothyroid
symptoms.
=
8
1
1
iO
+
THYROID HORMONE STARTED
‘
|
12
'
|
t4
F
16
CHRONGLOGICAL AGE { YEARS}
Figure 32. Relative patterns ofskeletal maturation (correlated with chronological age) in the two bovs who had
marked hypothyroidism. Comparison is with unexposed .
boys. Note the dramatic changein slope of growth curves
after thyroid hormone administration.