“ss i * 28 i i ,! —J T T STATURAL GROWTH SUBJECTS #3 & #5 ISOr- : VY 1 4 + 12 7 _ 140}—- £ 130}~ MEDIAN STATURE © | UNEXPOSED BOYS 5 120 <“ y 13h \s0 ! ~ 4 HOF— 4 100;- 7 THYROID HORMONE STARTED 30/— Bo | 3 | _| { 71 ~ ob 4 = + ax aL a gb a 4 a 2w 7 ol & o 4 d SKELETAL AGE o=0 HEIGHT AGE — SUBJECTNO.3 5 ---- SUBJECT NOS - _| 4 4 7 4 6 9 12 15 CHRONOLOGICAL AGE (YEARS) | y 6 a a i : a 8 ¢ J THYROID HORMONE STARTED J | J it 10 2 14 CHRONOLOGICAL AGE { YEARS) 4 16 Figure 31. Relative patterns of statural growth (corre- Figure 32. Relative patterns ofskeletal maturation (corre- marked hypothyroidism. Comparison is with unexposed. Note enhanced growthafter thyroid treatment. marked hypothyroidism. Comparison is with unexposed boys. Note the dramatic changein slope of growth curves lated with chronological age) in the two boys who had lated with chronological age) in the two boys who had after thyroid hormone administration. Figure 33. One of the two boys (#5) showing mostretardation of growth with developmentof hypothyroidism. Left: near the beginning of thyroid hormone Om A AH = we symptoms. fe showing remarkable spurt in growth and developmentwith dissappearance of hypothyroid wm: treatment (1966, age 13); right: after 3 years of treatment (1969), 0 \ ott i4 L - e :