A.
... ..
-

BEIR-I
1.

Cancer (Tables 3-3 and 3-4)
Derived
Cancer deaths/106 person rem
../”
i‘?.+
I
;.,
!-.,

Cancer deaths/year in U.S.
from 0.1 rem/year
(pop=

197,863,000)

Absolute

Relative

Absolute

Relative

516

738

26

37

30 year
elevated risk

1210

2436

61

123

lifetime
elevated risk

1485

8340

75

421

Leukemia
Other Cancers

Range

1726-2001

3174-9078

87-101

160-458

From the above the minimium estimate of cancer risk would be given by a
risk coefficient of 87/106 person rem and the maximum by 458/106 person
rem.

Thus, these two risk coefficients were used to define a range of

es-timated cancer deaths.

~-

2.

Gf5netic Effects (from Page 1 & 2 BEIR-1)
‘1

~

‘.:

Basecl on specific
,—- defects
.,

reproduc~l%e
generation would cause in the
,~-~~~~~~o—year
‘a
‘\i
(
first generation 100-1800 cases of dominant diseases and

defects per year (3.6 million births/year) or 5 times this
amount at equilibrium.
of 0.05% incidence
equilibrium.

The 1800 cases represent an increase

per year first generation and 0.25% at

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