38

bEFECTS ©}

and the severe, -potts epidermal igur. win
minimal dermal snjurs are wotabie.

RADIATION

fiw ted Na,

Ve pet

ncobiparmy animal lesions from known doses
vith desions i the exposed individitals in thits

ticulate nature ard cemevern qistmburion of te

-tady in order to estimate the skin dose, since

fallout material -vas responsible for the sports
nature of the lesions aud the daree compone
of soft energy beta mudlation was responsible
for the wreater epiderma: injury Vhe pros
nence of pigmentary anges is probabby ve
lated to race.* it is wenerally conceded that
blondes with dight pigment are more sensites.e
to radiation thar brunettes » 17)
Lastiy i -

-pectes differences in response may exist. and
ertila radition factors are not well estabmhed. such as accurate knowledge of the beta
~pectram of the fallout material and dose rate,

quite evident that sensitivity and

rFespatise

varied with anutome cocatrarn,

In Table 3.3 are listed the approximate sur
face skin doses required to produce recognizatie
epidermal injury fron beta radiations acim

( oiparison with human data suffers from wide

differences uy radiation energy and doses reported and methods of determining the rep
ose

Phe low meidence of infection of the radia-

Hen burns is probably due to their superticial
nature. Ulceration and partial healing preede d the time of minimal granulocyte counts.
~ copecelvable, however, that with higher

‘4

Table *.3,-—surtace Doses Required to Pri duce Recognizeable Epidermal Injury
SYESTIC 4 Th

ASTRA

Henshaw «* al 122

Rate

Raper and Barnes 123)
Snider and Raper (24)

Mice
Mice

Lushbaugh
Moritz and
Mor‘tz ane
Mor tz ana
Moritz wad
Mor tz ana

Sheep
Pies
Pigs
Pigs
Pigs
Pigs

Raper and Karnes | 23) .

—

js
pe
[37
ps
id
sr
sad
(ye?
{ql
sri
¥
\™

Ruts

Raper and Barnes 23)
+ 2h
Heoriques
Henriques
Heorigues
Heariques
Henriques

IOTOPE

Rabtt-

(26)
(26)
(26)
(265
(263

Mor tzaac Henriques (2H)

Las

AVERAGE
FNERGY
(MEV)

Woy
14
Wo5
m3
"5
443
Gi 5
add
i 2
3
ty
oT

SURFACE Dosk (REP)

1,
4+,
2,
2,
a,
2,
20,
4,
2,
1,
1,
i.

500-4, 00%)
O00
500
300
000
500-5, 000
000-30, OOO
000-5, O00
VOO—3, 000
500-2, 000
500-2. O00
500-2, 000

i eceeeneie ene

mals,

It is apparent from the table that beta

ray energyis of considerable importance in de

termining the degree of injury.

\ecording "4

Moritz and Henriques. ‘he difference in dase between that required te produce threshold skin

damage and that for permanent damage in pigs
is 500 to TOU rep

2h

fhe mm not pustined

Joses of whole-body radiation, the defenses
iwainst iafection might have been sufficiently
mpaired to have resulted in serious complicaSons from skin lesions of the severity encounered,

Severe radiation ingury is known to predispease tocuncer. The probability of the develop-

ihe nnd
* Reported
lesions

is

clinical

based

experience

predomiiantly

with
om

radiation ski

the

response

white-skinned peope Sheree fhe iexioms deseriberi
herein were obser. el Pita cd ovo oni tthe Muay rsip | pene
a highly pigmented

res ie

if nalienancies at the site of healed le-

ions os ankrioewn,

Certain factors appear to

dteerense che probability: (aj) The majority of
he

Jestaps were superterel,

(h) Visible signs

tourome radimtion dermatitis are absent in

Select target paragraph3