(LIN'CAL OBSERVATIONS eitis with prominent tvmonhoid follicles. fever of 99-100° F. during the urst day. and a puru lent nasal and tracheal discharge for about 1) days. It was of interest 'o determine whet het yNb) TREATMENT 2] Tante 2 2--URI and Changes in Granulocytes in Groups I and I] “UM BER w INDI- the appearance of URI could bes orrelated with: YIDUALS the dose of radiation rece vedios with chaperes in the leukocyte count Fifty-eight percent of the ndividuals in Group I and 56 percent of the mdividuals i: Group IT developed UR] Seventy percent of the affected individuals jevelopead syraptoms between the 27th and 32nd post-exposure davs. and the others developed <vmptoms in the subsequent 2 weeks. Fifty-seven percent of the affected individuals were observed to have an upward trend in their leukocyte counts, the increase being due primarily to granulocytes Since an increase in the mean granulocyte count of the entire population occurred about the 29th postexposure «tas. 1° seemed pertinent to determine whether in individual instances the imcrease was related te the oresence of respiratory infection. The relationship between the observed leuke cyte increase and the presence or ibsence of upper respiratory symptoms in Crroups FP oand II is shown in Table 2.2.) Seven of the 27 indviduals that developed both URI and a leukocyte increase developed the leukocyte increase 3 or more days before »smptorns of URE ue peared. It is also of interest that the rnedica! personnel involved in the sare and study of the radiated individuals had ia equa: incidence ane PRI mse on granuloeytes _RI no mse in granulocytes. —. So URI, rise in granulocytes... oo 0... 27 20 16 So TRI. vo rise in granuloevtes . . 19 branes Saal severity of respiratory infections. The inciieice and severity of respiratory infection in Crronp EM. which had received only shght radiarich, was the same as that in Group I and IT. Ce appearance of URI, therefore, did not appeair to be related to the dose of radiation or ros tianges n leukoevte level. 2.5 Comparison of Diseases Seen in Groups IJ and II With Those in Group IV Pie Diseases [Har were seen during the peruad of observation of Group J and II, which were exposed to the highest doses of radiation, ic» jisted in Table 2.3. None of the diseases ap- peared to be related to the etfects of irradiation, either directly or as a result of hematologic distucbances. For comparison, the diseases that were seen during the period of observation of is cup IV. which received the lowest dose of Table -.3-—Diseases That Were ¢ Ybserved in Groups I and I DISEASE “ MBER oF [NDI NUMBER OF INOI- IMSEASE VIDUALS Vil Cats Furuncle , GumAbscess Cholecystitis. Tinea Mittelschmerz_... Generalized urticar a Erythema multiforrie Migraine headache 2 \ i 1 | i one nitis Aphtnous uleer of tongue. = ond vlolisthesis _- Lape Toth extractions ‘Sastroenteritis yper respiratory confections bode ahar tor sillitus t I 1 5 . . 2 10 47 !