32 Table 16 Immunoelectrophoretic Analyses ~ Findings Subject Nos. Normal 15, 30, 20, 78, 8, 76, 92, 77, 9, 14, 33, 16, 2, 21, 57,47, 4, 37, 10, 73, 12, 914, 835, 838, 875, 844, 865, 896, 982, 836, 832, 936, 955, 956, 957, 830, 960, 939, 893, 979, 840, 833, 915, 967, 975, 882, 898, 1005, 868, 822, 1042, 841, 825, 885 Slightly increased y globulin precipitation-line 53,71, 86, 52, 63, 22, 32, 87, 59, 54, 79, 6, 66, 1, 45,928, 856, 883, 940, 1036, 944, 992, 858, 813, 864, 853, 887, 942, 829, 820, 828, 924, 961, 969, 895, 855, 884 Markedly increased y globulin precipitation-line Slightly increased precipitation-lines for £,,, 8,,,, and ¥ Markedly increased precipitation-lines for #,,, 83,, and y Markedly increased precipitation-linesfor £,,, and y Slightly increased precipitation-lines for §,, and y Markedly increased precipitation-lines for £,, and 862, 891 Slightly decreased precipitation-line for £3, Slightly increased precipitation-line for 84, Decrease of £,, and slight increase of y globulin 5, 900 29, 852 Decrease of f,, and y globulin precipitation-lines 60, 68, 824 precipitation-lines — Glucose-6-phosphate Dehydrogenase Activity and Hemoglobin Types Dr. Boyer at Johns Hopkins Hospital reported that all subjects examined had normal glucose-6phosphate dehydrogenase activity. On the starch gel electrophoresis al! were of a uniform glucose-6phosphate dehydrogenase electrophoretic type Class B. This is the type observed in all Americans of European ancestry and in 70% of Americansof mixed African and European ancestry. Electrophoretic studies of hemoglobin showed that al! Marshallese subjects examined had type AA. Blood Volume Studias During the 1961 and 1962 surveys, blood volume determinations, with use of Cr*!-labeled sodium chromate, were performed on 25 normal Micronesian and Caucasian persons living in the Marshall Islands for 1 yr or longer. Table 15 34, 75, 27, 817, 998, 888, B14 64, 958, 1035 829, 892, 1001 3,41 897 866 showsthe data for 23 of these on red cell mass and plasma volume based on body weight. From these data it appears that there was a significant reduction in red cell mass and/or plasma volumein 15 of 23 subjects, both Marshallese and Americans. During the anticipated 1963 survey, it is planned to repeat these studies in conjunction with estimations of lean body mass by use oftritiated water. Evaluation of the above results will be withheld until completion of the 1963 survey. Iimmunoelectrophoretic Studies Immunoelectrophoretic analyses were carried out on a number of Marshallese sera. These results are shown in Table 16. Dr. R. Biitler, who carried out these analyses, reported that “in summary we have found neither a paraproteinemia nor a typical picture of antibody-deficiency-syndrome. The high frequency of increases of some of the immunoglobulins is perhaps a typical sign of the investigated population.”