PRIVACY ACT MATERIAL REMOVED 31 T Table 15 le 14 Blocd Volume Studies (1961, 1962) Abnormal Chromosomes in Peripheral Blood Cultures Subject No. Total counts Dicentrics 64 10 2 59 —_— — LI 14 27° 24 26 30 —_— I 1 — _— 1-minute 50 69 — — —_ a — — — — 4] 58 69 79 80 27 32 19 19 16 —_— _ —_— Other Subject Race* Wt, lb C Cc Cc Cc Cc Cc Cc M M M M M M M M M M M M M Cc Cc Cc — _ —_ *Bone marrow smears showed 3 dicentrics on scanning. small amounts, however, and glycosuria was demonstrated only in those that showed urine clevations of 2+ to 4+. Four urines showed slight amount of protein, but other examinations did not reveal abnormalities which might be associated with proteinuria, Decrease, cc RBC Plasma RBC Plasma —_— —_— — _ — —_ _ — —_ 100 — — — —_ — — — 123 —_ _ — — — ~ 250 _— — _ — _ — — — — — — _ — _ — 100 — —_— — — — 100 100 400 550 350 250 250 250 — — 250 550 400 300 300 200 600 — 200 800 450 400 200 750 — 600 1000 600 100 500 500 100 — 100 600 _ 200 —_ 150 500 — 700 770 400 700 200 *C = Caucasian, M = Micronesian. Blood Sugar Determinations Fasting blood sugar analyses were carried out on 8 people (all in the unexposed group) who had shown urine positive for sugar on the previous survey. Of these, 4 showed elevated levels (Nos. 853, 884, 893, and 991). Non-fasting blood sugar determinations were carried out routinely on 72 people in the exposed and 125 in the unexposed groups. Elevations > 160 mg % were foundin 4 of these, | exposed (No. 29) and 3 unexposed (Nos. 932, 936, and 1042). The somewhat higherinci- dence of diabetes in the Marshallese people has been commented on in previous reports. Total Urine lodine and Creatinine The purpose of these analyses was to determine whether the rather high protein-bound iodinelevels reported in the Marshallese might be related to high iodine levels in the diet. Total iodine and creatinine analyses were carried out on 10 urine samples obtained from subjects who had previously shown relatively high protein-bound iodine levels. The levels for total iodine varied between 5.2 and 66.0 we % (av, 18.6), and the creatinine levels varied between 0.025 and 0.80 g/l (av; 0.52). Protein-Bound lodine Since previous survey results had shown protein-bound iodine levels on the high side of nor- mal, 14 sera were obtained on individuals for -fepeat analyses this year. The levels varied between 4.6 and 12.0 yg % with a mean of 8.6; these are again gencrally on the high side of normal. 158 105 153 161 165 156 110 172 150 138 155 122 102 10% 126 135 149 123 140 132 156 183 — Increase, cc These levels were considered to be in the normal range, although the creatinine levels were somewhat high because of alkalinity of the urine samples. Therefore it did not appear that the iodine in the diet could account for the generally higher protein-bound iodine levels observed. The cause of this slight elevation remains to be clarified. PRIVACY ACT MATERIAL REMOVED