| RG ES QOE ARCHIV IC ENERGY 326 U.S. i: Cottection: Box & |@ - F.C. Ss DEARBORN Se Folder OFMN 2- vor Biocoey ¢- MEDICE— | UNITED STATES ATOMIC ENERGY COMMISSION 4073 155 WASHINGTON 25, D.C. 3un~ ~ De FILE January 6, 1965 MEMORANDUM FOR cna TRMAN SEABORG " COMMISSIONKR BUNTING COMMISSIONER PALFREY COMMISSIONER RAMEY COMMISSIONER TAPE v TYROGGH CRNERAL manaceR f2-% ¢ Comagpicm~ JAN? R65 SUBJECT: FURTHER INFORMATION OM THREE MARSHALIXSE GIRLS OPERATED ON FOR REMOVAL OF THYROID NODULES (SEK ATTACHED COPY OF PREVIOUS MEMO, THIS SUBJECT). Dr. Robert A. Conard, Medical Department, Broekhaven National Laboratory, who has responsibility for conducting the clinical surveys, reports: "Sections of the nodules have been exemined by « number of pathologists including Drs. &.-Warren, G. H. Rlink, H. A. Jehnson and $. Lindsay. The concensus is that the nodules are benign, though with certain bizarre areas, and resemble iodine deficiency sdenomats." Dr. ‘Lindsay noted that the nodules in Jonge lap cases are similar to ones he has seen in children following LI therapy. This Division has a file of Dr. Lindsay's histological reports snd a review paper by Lindsay and Chatkoff, Cancer Research, 24:1099, 1964. The radiation dosages which these children's thyroidsa msy have received are being re-evaluated by Dr. John Gefmen's group, Lawrence Radiation Laboratory. It should be added that nodules in the thyroid glenda of young people frequently become malignant in the course of time. Therefore, while these which were removed promptly efter discovery were not malignant, there is 2 chance that in time they might have assumed neoplastic characteristics. February 1965. Dr. Conard’s next clinical survey will take place in € L. Dwnhan, M.D. Director Attachment: Division of Biology and Medicine Copy of memo dated 10/2/64 from C. L. Dunham to Chairman Seaborg BEST COPY AVAILABLE G