14

low excretors either heterozygous or homozygous
for the dominantallele. Striking differences in the
incidence of high excretors in various populations
have been demonstrated, and it appears thatthis
genetic polymorphism may be of considerable
value in anthropo-genetic investigations.”*'””
As a part of the study of the genetic relationships andoriginsof various Pacific peoples, this report extends observations on BAIB excretion to
the Micronesians inhabiting the Marshall Islands.
The fact that some of the Micronesians were ex-

carried out every year need be done only once

tion exposure can, temporarily at least, increase

of their cargo ships (Figure 9), which routinely
madethe roundsofthe islands for gathering copra, for carrying out the survey at Rongelap. Accordingly, for the 1960 survey the team consisted

posed to considerable radiation in 1954 is of
special interest here, since it is known that radiaBAIB excretion,”* and studies on the Marshallese

population mayelucidate possible long-term ef-

fects.

Urine samples from 65 exposed and 119 unexposed people (75.7% of the population ofthevillage) were collected in plastic bottles containing

thymolpreservative. The sexes were equally repre-

sented, and the ages varied from 3 to >/0 years.
In some cases several members of the same family
were included, and some kinships suitable for

genetic analysis were available. Eighteen samples

collected on Utirik were also studied. Urines were
kept at 4°C and shippedin refrigerated containers
to Seattle for analysis. These studies were carried
out by one of us (B.S. Blumberg) and Dr. S.A.
Gartler of the Department of Medicine, School of
Medicine, University of Washington. Studies were
completed 2 to 3 weeksafter collection of the specimens. Determinations of BAIB were carried out
by high voltage electrophoresis on paper,” and

creatinine was determinedbythe alkaline picrate
method.
Radionuclide Body Burden Evaluation
The methods used in the radionuclide body

burden evaluation are described later in a sepa-

rate section.

1960 Survey
BACKGROUND MATERIAL

The 1960 survey was reducedin size and scope
and limited to a very brief examination ofthe exposed people only. Several factors brought about
this change. The people had recovered to the extent that certain special examinationspreviously

every two to three years. In addition, as pointed
out before, the Trust Territory officials were concerned aboutthe slowness of economic recovery of
the Rongelapese and felt that the numerousvisiting scientific teams, particularly those with large
ships and crews, were partly responsible for the
unrest of the people and therefore requested that
the size of the surveys be kept to a minimum. It

was decided to defer the gammaspectrographic
analysis until 1961. The Trust Territory officials
agreed to greater participation of their medical

personnelin future surveys and to the use of one

of only one physician and one technician from
Brookhaven National Laboratory, and the re-

mainder of the medical group, arranged bythe

Trust Territory, included its Director of Public
Health, two Marshallese medical officers, and two

Micronesian laboratory technicians. The Director

of Dental Services and oneof his dental officers
also accompaniedthe team to carry out treatment
of the people. The District Administrator of the
Marshall Islands accompanied the team in order
to consult with the people on their agricultural
program.*
As in the previous year, several of the exposed
people nowliving at Kwajalein and Majuro Atolls
were examined atthese atolls prior to the Rongelap visit.
PROCEDURES

As in previous surveys, ¢xaminations were
carried out in the dispensary and the schoolhouse
in Rongelapvillage. Interval medical histones and
complete physical examinations were carried out
*Again in 1960, when the team arrived at Rongelap, the magistrate requested a meeting with the people. Theline of questions
and discussion was about the same as that reported for the previous year. Resistance toward the examinations was expressed by
only one or two of the people. Objections were again raised
against the ban on eating coconut crabs, which selectively concentrate Sr*° to such an extent that their consumption had to be
prohibited (Figure 4). The people were assured that these crabs
were being repeatedly examined and that, whenit was safe to
eat them, immediate notification would be given. Fish poisoning
apparently had been jess of a problem during the past year since
only one case had been noted, and the subject was not brought
up again. Following this meeting, cooperation by the people in
the examinations was almost complete.

Select target paragraph3