ABSTRACT
Absorbed dose D is shown to be a comnostte vartable, the vroduct of
fraction of cells hit (1.) and
cells.
OD is suitadle
organ.
cancer
cto cells
toa radiation ans it
since 1.5 1.5, DB approximates
the cell as well as
in tres
only Iy varies with D so
therefore does not mean
be lethal.
Rather,
_
that
fraction of cells
(nduction
trun a Shagle cell,
results in a wide uistrivution or
the expected mean value,
the
toa those
However, with low-level exposure (LLE) to radiation ana its
delivery of energy
and
because,
the mean energy density in
consequent provabdllicty of
and
(ait size) Z
for use with high level (ELE)
resulting acute organ effects
closely enough
the rean “dose™
a
the
z,
{1s constant with exposure.
nit sices
=,
Thus, sith Lit,
the apparent proportionality between “zose™
transfocmed is wtisleadiag.
that any (cell)
it means
stocrastis
Tnis proportiznalizy
dose, xo matter hew saall,-sac
that, in the exposure of 4 copulation 2
individual organisms consisting of
the coustituent relevant cells,
there
is
a small probability of particle-cell intecactions which tirunsler enerzy.
The probability of a cell transforming and
initiating a cancer
can imly
_
:2
greater than zero if the hit size (“dose of energy") to te cell is larze
enough.
Otherwise stated,
biologfcal organization,
to
that cell
the “dose”
namely,
tis ef
rh
4a5se z
if
ane
tve.
{is
definea at the proser
the cell and not
the organ,
ae
The above lrecen
develop a drastically diiferent approach
3S
as
are
q
.
only 2 larl<
to evaluation of
present system: absorbed organ dose, LET, a sta.idard raciation,
sog7uys
7
Lt
erty
that holds promise of obviating any requirement fur the coaponents sf
dose equivalent and rem.
q
aftVEa
the
KEL =),