DR. THOMAS ELY was then introduced by DR. SHILLING to discuss the chemical
phase of toxicology.
He spoke of the work being done at on-site laboratories in insoluble uranium, beryllium, fluorides, rare
earths, mercury, indium and polyphenyl compounds (such
TOXICOLOGY
as used in organic moderators).
At offsite laboratories,
work was being done on rare earths and nickel carbonyl.
He also spoke briefly of the Toxicological Information
Center which he had discussed at a previous ACEM meeting.
DR. SHILLING then introduced DR. DAVID BRUNER to discuss the radiation
aspects of toxicology.
Dr. Bruner spoke of animal studies being made
with so-called internal emitters.
There are two general groups of internal
emitters being studies the so-called standard materials such as iodine,
phosphorus and gold and also studies involving other uses of isotopes
in medicine, tritium as an inhalation hazard, radium and thorotrast.
At the conclusion of Dr. Bruner's presentation there was a general discussior
of the subject of toxicology and the meeting was adjourned at 5:25 p.m..
The meeting was called to order on Saturday morning at 9:00 a.m. by
DR. WARREN.
The first two presentations had been carried over from the
previous day.
DR. JAMES HAGGERTY was introduced to discuss the cancer program.
He
stated that 8% of the budget was devoted to this program and was carried
out principally by ORINS, BNL, ACRH, University of
California (San Francisco), ANL, University of Rochester,
CANCER
PROGRAM
and several off-site locations.
He compared the AEC program
involving $3.4 million to the much larger NCI program
involving $58 million for 1958. In response to a question
by DR. WARREN, it was explained that the isotope aid program
now was not limited to cancer but was limited to research
and at present amounted to about $229,000 as a subsidy.
DR. DUNHAM stated that he was attempting to obtain a reduction in the
cost of radioactive carbon in order to stimulate its use.
The cost of
Cobalt-60 nad recently been reduced but it has not been subsidized.
There was a general discussion among Committee members of support for
education in cancer. MR. MARINELLI expressed the opinion that he would
like to see some of the fundamentals of carcinogenesis verified.
In
this connection he referred to the work done by Bloom using ultraviolet
radiation.
DR. WARREN said that sources of Strontium-90 of known strength
were not readily available for biologic experimentation, and suggested
that the Abbott Company or some similar organization be asked to offer
some standard sources.