DRAFT order to establish that this was better, accumulate enough cases, fraction. Let, proposition. because while you make your certain me start again, the cure was not an all You cured 50% of the cases, all of any one of them. you obviously had to known 60% you didn't cure them So in order to establish that you have to have a hundred or two hundred here, and then a hundred or two hundred over here and then you got kind of an improvement you're looking for, especially now, because the chances are you are perhaps curing almost all those who can be cured, course, in the early days, Germans, it. so to speak, Of when it was the French versus the the difference was tremendous, The Germans caused damage to the skin, Make it that simple. you see. you could see the French didn't. It didn't take any brains to see that. where you may get say treating a certain kind of Now, cancer with a certain regime you get 40% cure. Now you want to go on and improve that, and what kind of improvement are you looking at? Well, if you get only 50% or 60% well in order to get the difference between 40% and 60% on a firm basis you have to start with a large number of patients. That is perhaps a 100, 200 patients here and a 100 200 patients there. That was one reason why I felt that pooling or establishing a joint center for radiation therapy at Harvard would give you these large groups who had been treated in a relatively uniform way, can't, so that comparisons could be made. just think in radiation therapy there might be, there are ten kinds of cancer to be treated. patients a year, of these kinds of You I'll say You only have 300 you might only have plenty of patients, each one distribution is a little different with them. 30