12 Hematol T. KUMATORI order of 350R to ‘ and LALANNE, C. M., logie, 6, 561, (1963) Ionizing Radiation Kira, K., Ikepa, N., Kimura, K., Kawanisut, H. and Kimura, M. (1956): ibid. I, 521. “Koyama, Y., Kumatort, T. et al. (1955): Iryo, 9, 1. Kumatoal, T. and Mryosut, K. (1963): Diagnosis and Treatment of Radioactive ietic tissue, Int. A (1967)). Poisoning, 253, International Atomic Energy Agency, Vienna. Kusatoai, T., IsHtHarna, T., Uepa, T. and Mrvosui, K. (1965): Medical Survey of We have compar the curves of Yu Japanese Exposed to Fallout Radiation in 1954—A Report after 10 Years, cases, and here at National Institute of Radiological Sciences, Chiba. same difference, @ tion of these data the difference bet: Mikamo, Y., Mryosui, K., SHimizu, K., IsHixawa, K., Kurryama, S., KoraMa, Y. and Kumatort, T. (1956): Research in the Effects and Influences of the Nuclear Bomb Test Explosions, II, 1313, Japan Society for the Promotion of Science, cases and the p atients was that Tokyo. of Hematology, lL, 29, Pan-Pacific Press, Tokyo. Swe te patients the dose with a maximum ° minus 4 per cent, “i Mivosu1, K. and Kumatoat, T. (1955): Acta Haematologica Japonica, 18, 379. Miyosut, K. and Kumatort, T. (1962): Proceedings of 8th International Congress of accidents the u Mivosut, K. and Kumatort, T. (1964): Nihon Ketsuekigaku Zensho, 3, 660, less, and of the o Maruzen Co., Tokyo. Dr. KuMaTORI: opinion. DISCUSSION damaye. and its relationship to external or internal radiation exposure? most cases. In our cases, we used Duke’s method. The bleeding time is normally 3 minutes, and in 1 or 2 Dr. KuMaTori (Japan) : Since this fatal case was anemic and revealed bone severe cases the bleeding time at the critical stage was as long as about 10 minutes. IJ think this came back to normal at about 10 weeks or so after titis can’t be ignored. correct data here. Dr. Sanc: And how about the fib- marrow aplasia, he received blood transfusions. Therefore, serum hepaHowever, at the same time the existence of radiation-induced liver damage should be considered. At present it is difficult to decide the cause of his liver damage. We should consider the probability of the radiation-induced liver damage, because in some publications we can see a similar histological picture of the liver of a patient who wasirradi- ated therapeutically. Dr. Sanc (Korea): I thank you Dr. Kumatori, I would like to ask you something about hemorrhagic tendencies on these cases, Would you tell me how long did hemorrhagic tendencies continue after the irradia- the exposures, though [ have no rinogen concentration? Dr. Kumatori: Fibrinogen concent- ration was almost normal from the beginning of the examination. Dr. Tupiana (France): I would like to ask Prof. Kumatori if be has an idea of how uniform was the dose delivered to your fishermen. I ask you this question because we have a rather large experience of total-body irradiation for mostly kidney transplants in human patients, and there are 2 main differences between your results and the one we have also. The first one is that aplasia of the blood occurs much earlier in our ‘severe. The prolongation of the bleed- patients, and the rigidity also occurs much earlier. The 2nd one is that the minimum number of leukocytes is much smaller in our cases, being of You can see normal bleeding time in cubic millimeter, after a dose of the tion? Dr. Kumatoat: In my cases the hemorrhagic tendencies were not so ing time was observed ina few cases. the order 1 doospea i ® if HD ae SA ila Dr. CLtrTon (U.S.A.): Concerning the one fatality, would you care to comment on the nature of the liver to 200 leukocytes per j In my