unknown cause. There was no diabetes, and his urinary sediment showed red cells, casts and protein. The serum creatinine was 3.4 mg/dl. He had chronic venousinsufficiency in the legs and a left hydrocele. A serologic test for filaria was negative. .There was also a mild macrocytosis; a serum B12 level was low normal. The cause of death is not known. Subject No. 6. This 69-year-old man died on Ebeye in 1989. His medical problems in March 1988 included diabetes (status post leg amputation) with chronic renal failure, severe neuropathy, and eye infection from recent cataract extraction, for which he was referred. He was moderately anemic with a Hb of 9.6 g/dl. The cause of death is unknown. Subject No. 7. This 42-year-old man died on Majuro in 1989. He had diabetes, extremely carious teeth, a cataract, and a disabling arthrogryposis. When last seen in 1989 his only medication was glyburide. His blood count and serum creatinine were normal, He wasreferred for cataract surgery. The death certificate lists overwhelming sepsis and severe pneumonia as the cause of death. Subject No. 8. This 89-year-old woman died on Ebeye in 1990. No important medical problems were noted when patient was last seen in March 1988. She had severe kyphosis, cataracts, and perhaps a mild dementia, but in general annual examinations indicate she was usuaily in quite good health. Her blood count was normal and a Papanicolaou smear was Class I in 1988. Medications included only acetaminophen and a skin antifungal agent. The cause of deathis unknown. Subject No. 9. This 76-year-old woman died on Ebeye on December 31, 1987. The death certificate diagnoses were cardiac failure and bronchitis. At the time of her last complete medical examination by the Brookhaven team she had a moderately severe anemia (hemoglobin level: 8.8 g/dt) and recent weight loss. The mean corpuscular volume was 98fl. and there was some hypersegmentation. A serum B12 level was somewhat low (170 pg/ml), but the urine methylmalonic acid level was normal at 0.8 ug/mg creatinine. Nevertheless, she was intramuscular B12. Mammography was her Papanicolaou smear wasclass I. relevant that her husband had died recegtly, andit is possible that he had advanced tuberculosis. Subject No. 10. This 59-year-old mdn died on Ebeye in 1990. He had advanced diabetfs mellitus with nephropathy, retinopathy, and neuropathy. When last seen in March 1990 his creafinine was 12.4 mg/dl and the hemoglobin level wag 10.4 g/dl. A HbAIc level was 6.8%, only slightly elevated. Flexible sigmoidoscopy was negative in 9987, and a chest x-ray at that time showed no actife disease. He was being followed by the Diabetid Clinic on Ebeye. His death certificate listed renal Failure due to diabetic nephropathy as the cause of Heath. Subject No. 11. This 61-year-old mag, a former heavy smoker, died on Majuro in 198@ He was known to have chronic renal insufficiencythoughtto be due to diabetes. He was referred 1987 for evaluation of this problem. An examination by the Brookhaven team calculi or hydronephrosis; renal siz normal. He had gout, and the renal di he had lost much weight and a hilar masf was noted on chest x-ray. He was referred for fevaluation. Carcinoma of the lung was indicated certificate. his death Subject No. 12. This 73-year-old woman had breast cancer diagnosed in 1985 afta@r a breast nodule was detected during her annial medical program physical examination. A mast#ctomy was done that year. She died in 1991. Whdn last seen by the medical team (March 1989) thEre was no evidence of metastatic disease, and tlfe death is unknown. cause of Subject No. 13. This 64-year-old woman died on Ebeye in 1988. Her last complete examination was in 1986, when hej problems included insulin-dependentdiabetes mel§tus, urinary tract infection, and abnormal liver fugction tests. Whenrepeated, the latter showed only minimally