ea Aodienits a a a ee A mle elietefli Me Ra An oth ™ stone: Table 20 Growth and Thyroid Studies in Subjects With Thyroid Abnormalities Neck 1327 Growth abnormality Year tested age, yr Skeletal ranking, yr Statural —ranking,° percentile 3 M_ Atrophy 1965 13 3 <10 5 M_ Atrophy 1965 13 5%. <10 1966 1966 Pre Post TSH TSH Serum iodine, ug PBI 1.4 08 1.9 0.8 3.2 8 3.1 17 F Nodular goiter 1965 1966 15 13%2 90 6.8(°64) 1.8 21 F Nodular 1965 15 15 10-25 8.1 (764) 69 F Nodular goiter 19654 1966! 16 16 2 M_ Nodular 1965 13 112 25-50 20 M_ Nodular 1965 19 Adult 25-50 72 F Nodular goiter 1965 18 17H2 >90 42 F Nodular goiter 1965 1966 15 13%2 10 61 F Nodular 1965 20 Adult 50-75 54 M_ Noedular 1965 13 13 90 19 M_ Nodular 1965 17 15K2 10 36 M_ Nodular 1965 19 18 75 4.1 33. *F Nodular 1965 13 13%2 >90 7.0 65 F Nodular 1965 13 10%2 <10 59 F Solitary nodule 1965 1966 35 64 F Carcinoma 1965 31 40 M Solitary nodule 1965 40 goiter goiter goiter goiter goiter goiter goiter goiter goiter 1966? 1966¢ 1966 1966 19664 1966 1966 1966 19664 . >90 6.5 18 (29) (23) (31) (31) T,1 1.0 Serum TSH, ng/ml >120 159 119 1.8 248 <0.5 372 1.3 <0.5 440 7.1 5.7 1.7 125 7.9 4.2 65 4.2 5.2 2.6 9.6 26.6 23 (15) (24) 57 4.6 12°(10) (24) 7.9 4.9 8.3 19 (24) (9) (14) 7°(20) (38) (19) (28) 17 ‘ <3 9.0 4.3 <b? 3.9 3.3 <17 4.3 <17 3.9 3.8 197 4.9 2.1 8.2 8.6 5.3 4.8 4.2 (16) <17 3.1 8.6 4.9 19 7.3 6.6 23.5 3.4 2.0 10.3 «Values in parentheses obtained at BNL. *Relative statural growth expressed as percentile ranking compared with growth curves of unexposed Marshallese children. “Assays in 1963 could not detect levels below 3 nanograms/ml. Seven unexposed children in the same age group had <3 ngyml. Assays in 1966 could not detect levels below 17 ng/ml. Three exposed children without thyroid disease (Nos. 6, 8, and 32) had <17 ng/ml. Two children exposed tn utero (Nos. 84 and 86) and two unexposed children had <17 ng/ml. The 1966 levels were obtained about 3 weeks after cessation of thyroxine therapy, the 1965 levels. before therapywas instituted. We are grateful to Dr. William Odell at the Nationa! Institutes of Health for carrying out these assays. ‘Post partial thyroidectomy. “While taking thyroxine. ae SHH g@29 fh SOC Sey aemee, eee and sex Thyroid Chronological Mince Subject No. at 4 hr,* % of dose