’ Ooo ‘ Plates 3.22 and 3.23 show lesions at 53 days post-exposure. Plate 3.22 (X100, H&E} (Case #75) Loose tamination of stratum corneum with outward papil- lary projections and resultant “rugose”’ uppearance. Stratum granulosum of good width. Basal and maipighian layecs distinct with pigment present. Slight edema of corium with mild telangieetisis and slight increase in perivascular lymphocytes and pericytes. Small, atrophic her follicle adjacent ta sebaceous gland-~— in mid pars reticularis. Plate 3.23 (X400, H&E) (Case #75) Same as 3.22. Occasional perinuclear cytoplasmic halos momid stratum granulosum. Loosely laminated stratum corneum, Pigment laden chromatophores in superficial corium along with occasional lymphocytes and mononuclear phagocytes. Plate 3.24 shows lesions (Seeond biopsy) at 46 days post-expogure. Plate 3.24 (X100, H&E) (Case #39) Narrow rugose epidermis with papillary extensions down- wird of stratum malphyi, Latter are heavily laden with melanotic pigment, Slight tolangi- cetasis of pars papilaris and pars reticularis of dermis. Occasional pigment laden chroma- Ot renee eee tophores in supe cficial dermis, oe one ee eo 2 of eee ee 2 oe eae 7 oe . . oe « «@ @ o one . ae ee ee eee . oe . 8h oe we © 00 6 » ee ee eve ae o° * eo . © cee oe © 0f oe ee 2 900 ae ee oe ee oe ef r wa cee eygee ft r re ) com COLOR PLATES