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Howard Brow

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L. W. Tuttle

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the effects of radiation constitutes a significant advance in the
field. Tha investigators found that the
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a aubstance which is widespread in most organiens and which multipls

fatty acids which are intiuately concerned withgrewth ani new osll
formation, when irradiated underge a shift of the isolated double
bonds into conjugated positions. This bamil shift is a measure of

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free radical and consequent peroxide formation in the acids molecules.
Appropriate calculations showed that thie pghenomencn takes place with
an ionio yield of 16 which ia very high and shoes that e chain reaction

similar to auto-cxidation must be taking place. Further experinents

are underway toward determining the nature of the reaction and its
products and a determination of the effects of these irradiated

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products upon living systema.

poam@ia to stetilizse food products by the use of irradiation frou

fission products.

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Related fundamental studies on the influence of

fonizing radiation upon pure organic metabolites and the effect of

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Information of this nature is of vital

importance in determining the possible hesardaz involved in the pro-

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Investigators at the University of California at Los Angeles projeat —
have recently made a very fundemental
concerning the
mechanism by which ionising radiation damages biological systens.
It is well known that dosages of radiation which exert profound
effecta upon living organisns have almost undetectable action on
moss pure chemical substances. For thia reason the
that

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JULY PROGRESS REPORT ~ MEDICAL BRANCH

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,

these radiation altered metabolites upon living systems has recently

been initiated at Reed College, Portland, Oregon; University of

_ California at Berkeley and the University of Michigan at Ann Arbor.

The objective of these studies is to provide basie information cone
cerning the safety or non-safety of the eonsumption of highly irradiated

food products prior to the time that the technologic feasibility of

using fiseion products to sterilize foods is established.
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By Commission action the Division of Blology and Medicine has been
given responsibility for the “soordination and sersening of proposals
from all agentes for biasedical experiments and eivil defense programs
as well as similar proposals from within the AEC organisation.
Recommended proposals will be referred to the Manager, SFO, through
the Division of Military Applications for comment on feasibility.
Acceptable and
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