32
Table 18

Correiation of Immunceiectrophoretic and Peripheral Blood Findings
With Age and Radiation Exposure!3 (D =decrease; I = increase)

Unexposed group
Change

Criterion

with age

Lymphocyte transformation
Serum proteins
Total serum proteins
Albumen

Total globulins

Alpha-i

Alpha-2
Beta

.

A (IgA)
D (IgD)

M (IgM)
G (IgG)
Kappa light chains
Lambda light chains

K/Lratio

Blood findings
_Hematocrit

D

0.89

- 11

0.68

I
D

35
45

- 15
+ 15.0

24
OL

I

37

—31.0

01

~ 18.3

OL

I

38

— 20.0
— 6.0

49
20

~17.0
— 3.0

75

I
I

I
I
I
I

.20
78
96
.24

D

I

01
.03

05
98

41

+ 0.4

7

+ 2.9

.07

31

- 0.1

65

— 8.4

Neutrophils

I

44

D

OL

_ 74
.22
.69
AS

712
43

D

( p value)

~ 4.0
— 3.0
— 3.0
— 14.0

I
D

Platelets

—17.1

.43
32

Sedimentation rate
Total leukocytes

Lymphocytes

Significance

from unexposed

I

Immunogiobulins

Percentdif.

with age (7 value)

I
I

Gamma.

Correlation

Exposed group

14

+11.4
—- 25

.08
59

—13.8

.04

51

.04

Table 19
Serum Proteins, 1973-1974

Group

Total protein.

Albumen

Alpha 1

Alpha 2

Beta

Gamma

Total globulin

Rongelap
Ailingnae

7.7620.70
7.99051

4,220.50
4.30+0.37

0.20+0.05
0.19-0.07

0.690.112
0.72+0.15

1.08%0.24
1.0540.20

1.590.41
1.76%0.38

3,540.58
3,600.56

Unexposed

7.600.71

4.1140.45

0.19*0.06

0.7540.14

1.00%0.24

1.5740.48

3.5220.54

Uturik

7.600.50

4.290.43

0.160.06

podiploid levels were related also to radiation;

this was more pronounced in the males, with the
exposed having 2.8 times as many hypodiploid
cells as the unexposed, whereas the exposed females had 1.3 times as many as the unexposed.
Polyploid levels were not found to be related to

radiation. Both sex and chromosomesize appeared as factors possibly related to hypodiploid

IO

cr

levels. In all subjects, regardless of sex or exposure,

124

0.69+0.30

0.890.23

1.67 0.45

3.332=0.50

the largest and most frequent loss of chromosomes
was in the G(Y) group (2.3 times expected loss). In
the CCX) group, females lost 15.2% more chromo-

somes than expected and males 12.6% less. No sex
or radiation effect was apparentin the otherfive
chromosomegroups. A series of additional cultures indicated the presence of chromosomebreakage factor in the plasma ofthe exposed subjects. In
cultures of the latter, chromosome aberrations

Select target paragraph3