32 Table 18 Correiation of Immunceiectrophoretic and Peripheral Blood Findings With Age and Radiation Exposure!3 (D =decrease; I = increase) Unexposed group Change Criterion with age Lymphocyte transformation Serum proteins Total serum proteins Albumen Total globulins Alpha-i Alpha-2 Beta . A (IgA) D (IgD) M (IgM) G (IgG) Kappa light chains Lambda light chains K/Lratio Blood findings _Hematocrit D 0.89 - 11 0.68 I D 35 45 - 15 + 15.0 24 OL I 37 —31.0 01 ~ 18.3 OL I 38 — 20.0 — 6.0 49 20 ~17.0 — 3.0 75 I I I I I I .20 78 96 .24 D I 01 .03 05 98 41 + 0.4 7 + 2.9 .07 31 - 0.1 65 — 8.4 Neutrophils I 44 D OL _ 74 .22 .69 AS 712 43 D ( p value) ~ 4.0 — 3.0 — 3.0 — 14.0 I D Platelets —17.1 .43 32 Sedimentation rate Total leukocytes Lymphocytes Significance from unexposed I Immunogiobulins Percentdif. with age (7 value) I I Gamma. Correlation Exposed group 14 +11.4 —- 25 .08 59 —13.8 .04 51 .04 Table 19 Serum Proteins, 1973-1974 Group Total protein. Albumen Alpha 1 Alpha 2 Beta Gamma Total globulin Rongelap Ailingnae 7.7620.70 7.99051 4,220.50 4.30+0.37 0.20+0.05 0.19-0.07 0.690.112 0.72+0.15 1.08%0.24 1.0540.20 1.590.41 1.76%0.38 3,540.58 3,600.56 Unexposed 7.600.71 4.1140.45 0.19*0.06 0.7540.14 1.00%0.24 1.5740.48 3.5220.54 Uturik 7.600.50 4.290.43 0.160.06 podiploid levels were related also to radiation; this was more pronounced in the males, with the exposed having 2.8 times as many hypodiploid cells as the unexposed, whereas the exposed females had 1.3 times as many as the unexposed. Polyploid levels were not found to be related to radiation. Both sex and chromosomesize appeared as factors possibly related to hypodiploid IO cr levels. In all subjects, regardless of sex or exposure, 124 0.69+0.30 0.890.23 1.67 0.45 3.332=0.50 the largest and most frequent loss of chromosomes was in the G(Y) group (2.3 times expected loss). In the CCX) group, females lost 15.2% more chromo- somes than expected and males 12.6% less. No sex or radiation effect was apparentin the otherfive chromosomegroups. A series of additional cultures indicated the presence of chromosomebreakage factor in the plasma ofthe exposed subjects. In cultures of the latter, chromosome aberrations