32
Table 18
Correiation of Immunceiectrophoretic and Peripheral Blood Findings
With Age and Radiation Exposure!3 (D =decrease; I = increase)
Unexposed group
Change
Criterion
with age
Lymphocyte transformation
Serum proteins
Total serum proteins
Albumen
Total globulins
Alpha-i
Alpha-2
Beta
.
A (IgA)
D (IgD)
M (IgM)
G (IgG)
Kappa light chains
Lambda light chains
K/Lratio
Blood findings
_Hematocrit
D
0.89
- 11
0.68
I
D
35
45
- 15
+ 15.0
24
OL
I
37
—31.0
01
~ 18.3
OL
I
38
— 20.0
— 6.0
49
20
~17.0
— 3.0
75
I
I
I
I
I
I
.20
78
96
.24
D
I
01
.03
05
98
41
+ 0.4
7
+ 2.9
.07
31
- 0.1
65
— 8.4
Neutrophils
I
44
D
OL
_ 74
.22
.69
AS
712
43
D
( p value)
~ 4.0
— 3.0
— 3.0
— 14.0
I
D
Platelets
—17.1
.43
32
Sedimentation rate
Total leukocytes
Lymphocytes
Significance
from unexposed
I
Immunogiobulins
Percentdif.
with age (7 value)
I
I
Gamma.
Correlation
Exposed group
14
+11.4
—- 25
.08
59
—13.8
.04
51
.04
Table 19
Serum Proteins, 1973-1974
Group
Total protein.
Albumen
Alpha 1
Alpha 2
Beta
Gamma
Total globulin
Rongelap
Ailingnae
7.7620.70
7.99051
4,220.50
4.30+0.37
0.20+0.05
0.19-0.07
0.690.112
0.72+0.15
1.08%0.24
1.0540.20
1.590.41
1.76%0.38
3,540.58
3,600.56
Unexposed
7.600.71
4.1140.45
0.19*0.06
0.7540.14
1.00%0.24
1.5740.48
3.5220.54
Uturik
7.600.50
4.290.43
0.160.06
podiploid levels were related also to radiation;
this was more pronounced in the males, with the
exposed having 2.8 times as many hypodiploid
cells as the unexposed, whereas the exposed females had 1.3 times as many as the unexposed.
Polyploid levels were not found to be related to
radiation. Both sex and chromosomesize appeared as factors possibly related to hypodiploid
IO
cr
levels. In all subjects, regardless of sex or exposure,
124
0.69+0.30
0.890.23
1.67 0.45
3.332=0.50
the largest and most frequent loss of chromosomes
was in the G(Y) group (2.3 times expected loss). In
the CCX) group, females lost 15.2% more chromo-
somes than expected and males 12.6% less. No sex
or radiation effect was apparentin the otherfive
chromosomegroups. A series of additional cultures indicated the presence of chromosomebreakage factor in the plasma ofthe exposed subjects. In
cultures of the latter, chromosome aberrations