With thease urvertain cbhservations uncind, a luboratecy experiment sin cost was cesimmad te tent tha akeve hypothesis. A preun of Th youn fomlie mist ides ciea to those used in cther radiation exparbacnis woroisenoome cf fourbesaca loveic Lf 131i which were Hace to cause relative ty mild depres Cf thyroid dbmice. Ter - oth ware bred to normal sales after ali 124i had disanpeured from th: hard. litic. were identifies wiih motherg aml Ledy weights cf iittes inales mendes. Tey nem. weaned whan appresinately "9 yuma, ted a diat with asequile dat sot Eiztens latins 2 oar sacrificed at about 256 ses ot Lorty weient. Tho thymids wee cetdpobeus) + diso~st Gut amdoagishedd., fomale ccomleois. Uhtce dare comaarid WEG, mata roa paiterg womb tocher JlatyL Mapeatend laittora Clore) werd oltabsed pen tle Boate: fo. acs co A paride i of ame cya crount il theism sermwsmtive calaeiditieau woavedb Ties te oo est that visaprias i.on the fanerled of the fuente three ea liatien dose Mbesls Clupa ee inereasiss, Uvyreid weichta hut tha obfreriss feud chs feurth oad sob heavy pean Somlics had thyrci: weight witen moé: naarly reserbied nertal conmtrpls tsis tht san Uniurlunately, ti nusber of animalg usest in Ghesea coteutinewit) wdo poral) ad the: ss haavily middated cotheort wens nat meadily imprestiit hoard todo Glplitier . fe out. Of tha maviost scue of radiation, these few ofispring did now fit phe pattem Gosninely establicned ty the lower lovels of Ue series. These exp Pepaiied. The questicn of the adolescent goiters in children of exposed Marshalicsa on eeneelap «as mr-expleral rere thoreucshly in the mst With tha previous incesplate cLservations in mi:d, ‘he presences of adolescents worm alter the fallout exposura was mevicwsd: in child mn of expose: = and wmexposced ponuluticn of Penselap, in a street survey of all rec le on Gtirix ivh: had received very icw level «xposure) and on a population of alrcut Ze on iikier wh. there: was no fallcut. Thence data on the presence cf diffuse thyrai eslac=smeni are. and history of purents! exposure are now being, analyvogl. It is cle Very usu anons tne Harcsnaillese and that when found. such gs cn often in individuals wtsce origin was half German cr Portuguese. * . THE STUDY OF MORFHOLOGIC CHASES DI I2AN THYPOILS PREVICUSLY TREATIO WITH 1411 Unfortunately for cur work, in the past yeer no patients who been treated with 131] cer hycerthyroidica and studied extensively srevicusl> m cur perserns_ series hive iid clinical cousen for thyrcid surrfer;, which would fe mit stucy cl hrs thyroid tissue. Oppertunities to cbtain such tissues For study ccciir fashica end onl; wren a sass develcrs which causes concern. Marshallese patients who - in a rantc=e There ere, however. the furnished material of this xind during thefpast ~~ THE RELATICNS:IP CP -s Arye pees _ oe wee tae SIT RPE NUCLEAR FORMS TD THE PERSISTIcr OF PATIETS TREATIO . CR GRAVES DISEASE ALD FREVICUSLY STUD Although we nartially nemve er partially destroy the excessiv thyroid in Graves' disease to correct hyrerthyrcidisn, the untmcwn Ls — yos> ’ a @rivirg force shnat makes tie thyroid cveructive trobahly continues fer a time. The requls of <uis driving force may b2 cerpurubic in some respects to the stimelus shih is cvsaten aan des Fae eet He by givin; antithyroid criss to nerme@l rats. We knew that antithyro to mats previcusity treated with 13517 mekes the Sisarre nuclear f evident. The sresence of bizarre nuclear forms in sare it treat and not in others ight 52 attributable to the centirued stimulus o