:

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.

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about 10 days, they were assumed to be in equilibrium with our diet and to

eliminate (as the average of our control group) 2 grams of K per day in the

urine and 0.5 gram per day in the feces. Knowing the K contents of the

samples collected, this assumption permits a not-too-far-fetched extrapo-

lation to the daily excretion rate.

The Zn® data are given in Table 10. An average of 6.7 tic of zn
per mic of Zn® present in the total body is eliminated with each gram of

K in the feces.

The Zn™ amount present in the urine is negligible.

On the

basis of 0.5 gram of K eliminated per day by the fecal route, 3.4 uc zn
per muc Zn® in the body would be eliminated per day. The biological
half-time for the element is thus 200 days. An effective biological half-

time of 110 days results by adding the effect of the physical half-life of
245 days. This is considerably longer than the published values.

TABLE 10

Subject
j

4

Feces

ze

Oe
no data

Urine

zn

Smee
-

3340

6

536

82

q

8

236

1340

-

42

7

183

-

5

10

280

Body burden

-

-

29.5

482

73

Hic Zn& per gram
in feces

mute Zn®*in body
7

.

7.4

62.1

3.8

29.5

6.3

229

29.5

K

59

9.7

average 6.7

bs
i
4s

PER,

Gt

.
The Cs'3" data on two subjects are given in Table 11; they similarly
are based on the American average of 2 grams of K eliminated in the urine
per day and 0.5 gram of K in the feces per day. The effective biological
half-time was 92.4 days for Subject 5 and 157 days for Subject 8. The
average of these values is in essential agreement with values found under
controlled conditions.

SO1Z13b

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