:
|
.
!
about 10 days, they were assumed to be in equilibrium with our diet and to
eliminate (as the average of our control group) 2 grams of K per day in the
urine and 0.5 gram per day in the feces. Knowing the K contents of the
samples collected, this assumption permits a not-too-far-fetched extrapo-
lation to the daily excretion rate.
The Zn® data are given in Table 10. An average of 6.7 tic of zn
per mic of Zn® present in the total body is eliminated with each gram of
K in the feces.
The Zn™ amount present in the urine is negligible.
On the
basis of 0.5 gram of K eliminated per day by the fecal route, 3.4 uc zn
per muc Zn® in the body would be eliminated per day. The biological
half-time for the element is thus 200 days. An effective biological half-
time of 110 days results by adding the effect of the physical half-life of
245 days. This is considerably longer than the published values.
TABLE 10
Subject
j
4
Feces
ze
Oe
no data
Urine
zn
Smee
-
3340
6
536
82
q
8
236
1340
-
42
7
183
-
5
10
280
Body burden
-
-
29.5
482
73
Hic Zn& per gram
in feces
mute Zn®*in body
7
.
7.4
62.1
3.8
29.5
6.3
229
29.5
K
59
9.7
average 6.7
bs
i
4s
PER,
Gt
.
The Cs'3" data on two subjects are given in Table 11; they similarly
are based on the American average of 2 grams of K eliminated in the urine
per day and 0.5 gram of K in the feces per day. The effective biological
half-time was 92.4 days for Subject 5 and 157 days for Subject 8. The
average of these values is in essential agreement with values found under
controlled conditions.
SO1Z13b