be the order oF 10-15 days for 1l- to e-year-old children and increases to ~ 100 days by age 20. adult life. It then remains reasonably constant throughcut The body mass is less for the younger azé ercups, and these two factors tend to offset each other in dose calculeticns. Doses to children are generally less than for ejults as a resuit of the corbination when the relative adistary intake is Therefore, estimates Yor adults are usually a conservative estimat go Sr — Reports by. Loutit, 15 16 : (D included, children receive a lesser dose than aculis. dose 14) of these two offsetting factors. 17 e . . 9 NdSr/g Ca in human bone is greater’ than 6 yr, including: adults. 90 “ -_ nm 4 am 4 ct However, the turnover rete is much more rapid and the retention time mach shorter for “Sr in aces 1-5. dose, and the dose ra 4 m pp Lt) ft Ur om Oo RH 4) fi 4 ct ts a) 4 J nm nq mo 7) ECi hy oO HY on The commitment resulting frem a specitied ingestion of ~ a4 aas7 . meen = ,—=tf . 2 ~ + ae resulting Gcse to chiicren, therercore, is not straishvrtirwara and is . ~ = om : ~ = . * . shee oO ae - a * 9 acpendent urcn the relative interaction of these two Tactcrs.” Any of these factors. as well as the difference in dietary intaxe. The mocel + Doerr OT 226 5 = = tinggi ft L a } repertec cy Bennett is thererore used, ror estimating whe doses te chisaren. 0 _ . . . LU-20 ingested 7 Sr are considered to be age invariant.” Bennett 16.goes | —, oa Ky © rH In, oO ) n f, oO ©) i ry' cl wy 4 64 Y ke c+ i} oe a w 4 rh oO iy hy 4]1 KH mY dS (D fu m ©) }-- < {> QO. bt mm O 4 Dose Models ena Diet Os 4. 5 & recent model Irom ol, model the child serarately from the adult. and this model is applied for estimating the bone doses te children. AWOS