be the order oF 10-15 days for 1l- to e-year-old children and increases to
~ 100 days by age 20.
adult life.

It then remains reasonably constant throughcut

The body mass is less for the younger azé ercups, and these

two factors tend to offset each other in dose calculeticns.

Doses to

children are generally less than for ejults as a resuit of the corbination
when the relative adistary intake is
Therefore,

estimates Yor adults are usually a conservative estimat
go

Sr — Reports by. Loutit,

15

16

:

(D

included, children receive a lesser dose than aculis.

dose

14)

of these two offsetting factors.

17

e

.
.
9 NdSr/g Ca in
human bone is greater’

than 6 yr, including: adults.

90

“

-_

nm

4

am
4

ct

However, the turnover rete is much more

rapid and the retention time mach shorter for “Sr in aces 1-5.

dose, and the dose

ra
4
m
pp

Lt)

ft
Ur
om

Oo
RH

4)

fi

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ct
ts

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7)

ECi

hy
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on

The

commitment resulting frem a specitied ingestion of

~

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aas7

.

meen

=

,—=tf

.

2

~

+

ae

resulting Gcse to chiicren, therercore, is not straishvrtirwara and is
.

~

= om

:

~

=

.

*

.

shee oO ae

-

a

*

9
acpendent urcn the relative interaction of these two Tactcrs.”

Any

of these factors. as well as the difference in dietary intaxe.

The mocel

+
Doerr OT
226
5
=
=
tinggi ft
L
a
}
repertec
cy Bennett
is
thererore
used, ror
estimating
whe
doses
te chisaren.

0
_
.
.
.
LU-20
ingested 7 Sr are considered to be age invariant.”
Bennett

16.goes

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4

Dose Models ena Diet
Os

4.

5

& recent model Irom

ol,

model the child serarately from the adult. and this model is

applied for estimating the bone doses te children.

AWOS

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