52 with marked growth retardation (Nos. 3 and 5). T, levels before surgery were lower in subjects exposed in childhood than in unexposed controls. Subjects exposed as adults who developed either benign or malignant thyroid lesions did not show notable impairment of thyroid function. The serum iodine levels of exposed and unexposed people for the past 15 years are given in Appendix 8. In 1965, the rates of urine and thyroid accumu- lation of 132] were measured over a 4-hr period in 21 Rongelap subjects, of whom 9 were unexposed and 12 were exposed as adults.!8 The data are summarized in Table 26. Compared with North American normal values obtained in 196518 (urine, Ag; 2; thyroid, Ag, 2=1; thyroid fraction 0.33), both the exposed and unexposed Mar- shallese showed slow urine and thyroid transfer rates of extrathyroid iodide but a high thvroidfraction. Similar studies done in 1972 on 2 Rongelapese without detectable thyroid abnurmalities. Table 28 Thvroid Status of Exposed Rongelap Subjects Without Recognized Thyroid Lesions, 1974 Subject No. Age and sex (1974) Plasma Ts, pe/dl Pre-TSH 24 hr post-TSH Increment* Plasma TSH,** pU/ml TBG- binding capacin. pe T, dl 4+M 6M 7M 58 21 36 6.9 6.8 4.7 7.8 8.3 3.3 0.9 15 0.6 7.0 3.9 2.1 18.3 9M +2 4.5 3.3 0.8 4.5 9.1 10M 12 F 16M 24F 34 F 35M 37 M 39 F 41M 48 F 51F 66 F 68 M 70 F 73 M 76M 78 F 80 M 81 F 82M 83 M 85M . LF 11M 14 F 22F 27M 44M 38 F 63 F 67 F 71 F 32 M 47M . Mean = S.D. 44 38 39 33 65 33 40 35 64 26 45 52 64 35 38 3l 37 66 28 70 20 20 9.2 6.5 6.4 8.2 7 39 4.6 8.3 6.0 7.2 6.9 7.0 8.9 7.9 7.8 5.4 6.3 8.1 5.8 5.8 6.2 7.8 74 5A 70 45 37 36 24 79 56 34 48 24 28 12.8 8.7 8.3 12.1 10.6 78 6.6 11.5 9.4 12.2 9.1 9.4 10.4 11.8 12.0 7.0 7A 9.1 78 6.7 8.6 11.4 3.6 2.2 19 3.9 3.5 1.9 2.0 3.2 3.4 3.0 2.2 2.4 1.6 3.9 4.2 1.6 0.8 1.0 2.0 0.9 2.4 3.6 *Normalin 13 Pittsburgh subjects: 4.7 1.0 ug/dl.8 14.4 16.7 21.7 184 186 233 212 1.4 68 6.7 35 75 58 8.2 8.2 7.4 4.2 75 84 6.61.7 <1.0 4.4 5.3 4.4 6.3 3.1 2.6 3.1 4.4 3.2 39 3.1 6.0 13 2.3 4.7 8.8 3.0 3.4 3.8 7.0 2.3 3.9 3.0 2.7 2.7 4.2 5.3 6.3 2.7 10.3 <1.0 7.0 2.3521.2 **Measured in pre-TSH samples. Normal is (3 ul ml