52
with marked growth retardation (Nos. 3 and 5).
T, levels before surgery were lower in subjects exposed in childhood than in unexposed controls.
Subjects exposed as adults who developed either
benign or malignant thyroid lesions did not show
notable impairment of thyroid function. The
serum iodine levels of exposed and unexposed
people for the past 15 years are given in Appendix 8.
In 1965, the rates of urine and thyroid accumu-
lation of 132] were measured over a 4-hr period in
21 Rongelap subjects, of whom 9 were unexposed
and 12 were exposed as adults.!8 The data are
summarized in Table 26. Compared with North
American normal values obtained in 196518
(urine, Ag; 2; thyroid, Ag, 2=1; thyroid fraction
0.33), both the exposed and unexposed Mar-
shallese showed slow urine and thyroid transfer
rates of extrathyroid iodide but a high thvroidfraction. Similar studies done in 1972 on 2 Rongelapese without detectable thyroid abnurmalities.
Table 28
Thvroid Status of Exposed Rongelap Subjects Without Recognized Thyroid Lesions, 1974
Subject No.
Age
and sex
(1974)
Plasma Ts, pe/dl
Pre-TSH
24 hr post-TSH
Increment*
Plasma TSH,**
pU/ml
TBG-
binding capacin.
pe T, dl
4+M
6M
7M
58
21
36
6.9
6.8
4.7
7.8
8.3
3.3
0.9
15
0.6
7.0
3.9
2.1
18.3
9M
+2
4.5
3.3
0.8
4.5
9.1
10M
12 F
16M
24F
34 F
35M
37 M
39 F
41M
48 F
51F
66 F
68 M
70 F
73 M
76M
78 F
80 M
81 F
82M
83 M
85M
.
LF
11M
14 F
22F
27M
44M
38 F
63 F
67 F
71 F
32 M
47M
.
Mean = S.D.
44
38
39
33
65
33
40
35
64
26
45
52
64
35
38
3l
37
66
28
70
20
20
9.2
6.5
6.4
8.2
7
39
4.6
8.3
6.0
7.2
6.9
7.0
8.9
7.9
7.8
5.4
6.3
8.1
5.8
5.8
6.2
7.8
74
5A
70
45
37
36
24
79
56
34
48
24
28
12.8
8.7
8.3
12.1
10.6
78
6.6
11.5
9.4
12.2
9.1
9.4
10.4
11.8
12.0
7.0
7A
9.1
78
6.7
8.6
11.4
3.6
2.2
19
3.9
3.5
1.9
2.0
3.2
3.4
3.0
2.2
2.4
1.6
3.9
4.2
1.6
0.8
1.0
2.0
0.9
2.4
3.6
*Normalin 13 Pittsburgh subjects: 4.7 1.0 ug/dl.8
14.4
16.7
21.7
184
186
233
212
1.4
68
6.7
35
75
58
8.2
8.2
7.4
4.2
75
84
6.61.7
<1.0
4.4
5.3
4.4
6.3
3.1
2.6
3.1
4.4
3.2
39
3.1
6.0
13
2.3
4.7
8.8
3.0
3.4
3.8
7.0
2.3
3.9
3.0
2.7
2.7
4.2
5.3
6.3
2.7
10.3
<1.0
7.0
2.3521.2
**Measured in pre-TSH samples. Normal is (3 ul ml