38 the blood volumes and the red cell volumesof the Caucasiansliving in the Islands and the Caucasians of the Siri and Moore groups; furthermore, dura- tion of residency in the Islands has nosignificant effect. Earlier data had suggested that Caucasians living in the Marshall Islands might have reduced blood volumesandred blood cell volumes. Though this may be true for certain individuals, it does not seem to hold true for the group as a whole. Test for Australia Antigen The Australia antigen, a serum protein first detected in the serum ofthe Australian aborigines, was searchedfor in the Rongelap popuiation.* Details of these studies are presented in Appendix 16. Samples of sera from 250 Rongelap people were examined between 1958 and 1965. Ofthese, 237 were consistently negative, 11 were consistently positive (4.4%), and 2 were inconsistent. Family studies indicated that positive subjects were homozygousfor the genes. This antigen has been found to be relatively commonin someformsofleukemia. *These studies were carried out by Dr. B.S. Blumberg, Insti- tute for Cancer Research, Philadelphia, Pa. Since the Rongelap people will be medically examined for manyyears,it will be interesting to see whetherthe presence of this antigen is related substantially to disease, particularly leukemia. ESTIMATION OF INTERNAL BODY BURDENS OF RADIONUCLIDES In the 1965 survey, the body burdensofradionuclides were determined by use of a portable shadow-shield type of whole-body counter and by radiochemicalanalysis of 24-hr urine specimens. Whole-Body Counting The use of the shadow-shield type of whole- body counter represents a departure from previous surveys, in which a 21-ton steel room had been transported to Rongelap and used for this purpose. Correlations between the two techniques were established by standardizations using the permanent steel room anda duplicate of the shadowshield at Brookhaven National Laboratory. The body ‘°K values of the Rongelapese provide another means of correlation. The shadow-shield counter (Figure 68) is very similar to the one described by Palmer and _ Roesch*® and to the Hanford whole-body counter.’® It was installed on Rongelap in one of the _— REGRESSION LINES sini { BV =0.91+0.090 (Taw) RCV =0.08+00474 (TW) BY :0647+0115 (TBW) MOORE { RCV «0.158 +0,.05296 (TBW) AV :0.5337+00767 (TBW) MARSHALLESE { RCV = -01749+ 0.044) (TBW) | CAUCASHANS iN PACIFIC BY = 1.210140 0792 (TBW) RCV =019947+0 0419 (TBW) 7 , Z / system was Calibrated with a plastic phantom man, both in a stationary position beneath the counter and with movement equivalent to the length of the body during the count. The signal from the detector was picked up by 7 photomultiplier tubes mounted on thecrystal, and _ b VOLUME, LITERS lead bricks, and is movedto a position underthe detector by a motor-driven worm-screw drive. The ; | 1 the gamma-ray spectrum was analyzed with a 400-channel pulse-height analyzer (RIDL). The gamma-ray spectral data were read outonrolls of im [ | I o supported by steel plate about 14 in. above the bed. The subject to be counted lies on a foam rub- ber cushion in the trough between the two walls of | i newly acquired air-conditioned trailers. The detector, an 114-in.-diameter Nal (T}) crystal 4 in. thick (Harshaw), is housed in a lead shielding * of eae Z-"" F MOORE J 10 20 seeeeee MARSHALLESE 30 —-— CAUCASIANS IN PACIFIC { | 40 50 TOTAL BODY WATER, LITERS Figure 67. 60 adding-machine paper for immediate evaluation, and on punched papertapefor subsequent data processing which involved transfer of the data from the punched papertape to magnetic tape and subsequent analysis in termsof radioisotopes by a spectral stripping program on an IBM-7094