. Project Title: 17. Exposure to External and Internal Radiation In Vivo Measurement of Radionuclides in Man; Body Burden and Kinetic Factors, Compurer Applications Expected Results in FY 1974: (Cont'd.) RX-01-01-(b) accumulate Statistically significant data on the K12 strain grown under control conditions tions, (normal background) and under reduced background radiation condi- The latter will include the use of K-40 free growth media. A CRT data terminal will be interfaced with the Sigma 2 to improve the program editing capabilities. A multi input interface and rebuilding of the monitor is planned for better communication with users, It is planned to improve the access to BROOKNET from the EPR keyboard and to provide direct access to BROOKNET from the whole-body counter. (Robertson) 18. Expected Results in FY 1975; o* The general objectives will remain the same with modifications based on current findings and development of advanced techniques. The emphasis will be on those clinical applications in which the technique of neutron activation will play the essential role. (Cohn) Consideration will be given to related experiments with other organisms to study the role of natural background in producing the normal mutation rate. It is expected that Drosophila will probably be the highest order species that can be used because ot the problem of having sufficient numbers for statistical significance. 19. Description and Explanation of Major Materials, Equipment and Subcontract Items: FY 1975 Capital Equipment: Specific costs for these studies include replacement of two multichannel analyzers one at $10,000, and one at $14,000, Miscellaneous instrumentation equipment, power supplies, amplifiers, recorders, and scalers and two terminal stations for information retrieval and input is estimated at $20,000. 20. Proposed Obligations for Related Construction Projects: ree a (See Continuation Sheet) 1119182 RX-22