Biological Studies of Materials Arising from Energy Qperations
Project Title:
Interaction of Chemicals with Nucleic Acids
RX-0 3-06-(b)
18,
Expected Results in FY 1975:
(Cont'd,)
is expected

that the survey of classes of compounds directly interacting

with DNA and other nucleic acids and their availability as pure compounds
will be completed in the first year.
In addition, a number of these
interactions will have been studied in vitro by various physico-chemical
techniques,

The determination of the molecular interaction by x-ray

diffraction and model-building is a more time consuming process, and at

most,
19.

several complexes may be determined in a year,

Description and Explanation of Major Materials, Equipment, and
Subcontract Items:
None

20.°

N

Proposed Obligations for Related Construction Projects:

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None

RX-388

11719331

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