38
phosphatase stainttPot neutrophils showed a generally normal disse:bution of positive cells, as in
the previous year. Basophil counts of 4000 cells

showed no increase in levels above the normal percentage in anv subjects, either exposed or unexposed, in the 1959 and 1960 surveys, except for
one 6- year-old exposed boy ( =3).* The mean

cent vears. However, the total absence of anti-

bodies even in persons over 40 suggests the pos-

sibility that it has not occurred in this population
at all. but the first interpretation is equally good.

The same comments would refer to the CA virus

or parainfluenza 2, but here'the morelikely interpretation is that the virus has not been present in

percent basophil count (counting 4000 whitecells)
for tHe exposed Rongelap group was 0.42% in
1959 and 0.93% in 1960; in the Ailingnae group,
0.29% in 1959 and 0.80% in 1960. Basophil counts

the recent past, but the presence of antibodies mav
suggest that it had been present 16 or more years
earlier. Since there is some overlap in antigens and
antibodies between mumpsand the parainfluenza
group, the CA reactions and/or the mumpsreac-

phatase and basophil counts are presented in

with other members of the parainfluenza group.
“It would be interesting to find out to what extent the psittacosis group and fever represent a

on the unexposed group are not yet complete for
1959. The individual values for alkaline phes-

Appendix 5.

Complement Fixation Tests
The resuits of the complement fixation tests are
shown in Table 23. In discussing these results Dr.

R. J. Heubner made the following comments:

“T suppose the most interesting thing is that

there is evidence of infection with almost all the

tions could conceivably merelyreflect infections

threat to this population, and of course in the

birds and domestic animals as well.”

Dr. Heubner’s forecast of A:...n influenza in the
Marshall Islands from the Rongelap data is interesting in that an epidemic of serious proportions

did occur at Kwajalein Atoll in January 1960 re-

groupsof viruses that wetested for. It is important

sulting in significant mortality.

generally less persistent than are hemagglutina-

groups in the exposed people were, in nearly ail
cases, lower than in the corresponding unexposed

to point out that complement-fixing antibodies are

tion inhibition and neutralizing antibodies. There-

fore, the high levels of adenovirus and HA | com-

-

The average antibodyutersfor the different age

age groups. It is not known whetherthisis a sig-

plement-fixing antibodies reflect either recent in-

nificant finding; further studies will be done to
determine this. At three years after exposure, the

low levels obtained for other agents, such as influ-

slightly less in the exposed people than in the un- °

fection or multiple infections with various members of the parainfluenza family of viruses. The

enza A, influenza B, HA 2, CA, mumps, LGV,
and Q fever mayreflect low levels of infection with
these agents, but more likely might reflect the fact
that such agents have not been prevalent in recent
years. Thus, one might conclude from the data
that the Asian influenza virus has not yet seriously

primary response to tetanus antitoxin averaged

exposed.? However, because of the small numbers
of people studied, this finding could not be considered significant.
Sodium and Potassium Levels, 1959

Potassium intake appeared to approximatethatof
Americans, namely, 240 to 100 mEq/day. Salt

involved the Marshall Island populations, orelse,
of course, that the complement-fixing antibody

intake varied widely as judged by urine excretion,

‘“T would rather suspect from the age distribu-

salt consumption of someindividuals is undoubt-

produced by the Asian influenza hasnotpersisted.

tion that Asian influenza still has not reached
these people, and that one might look forward to

see if they are involved at some future date. Similarly, the age distribution of influenza B antibodies suggests that it has not occurred for at leasth

6 to lO year: “Phe absence of HA 2 antibodies suggests thatt
virus has not been prevalent in re-

*In 1959 his basophil count was 2.1%, WBC 8600, and alkaline phosphatase negative cells 79%. In 1960 his basophil count
was 3%, WBC 6100, and alkaline phosphatase negative cells
70%. No abnormal forms were seen.

ranging from 2 to 18 g/day. The relatively high

edly related to the irregular consumption of

canned C rations, to which 2% NaCl is ade -!
routinely during preparation. The median int..€

of salt appeared to approximate that of male em-

plovees at Brookhaven National Laboratory,
namely, 10 g/day. This undoubtedly represents
an increase over the intake in earlier years when
onlv native foods were eaten. It will be of interest
to note whetherthe incidence of hypertension also
will begin to increase. At present the prevalence

of hypertension (B.P. greater than 140/90)is 9.2%

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