50

types.®7 For the three major pathogensfound,the

overall infection rates were: Entamoeba histolytica,
18.2%; hookworm, 5.5%; and Trichurts trichiura,

34.3%.
Eosinophilia (>> 5%) has consistently been noted
in about half the people. The fact that half the
cases with eosinophilia showed no helminthic infections at all suggests that other factors besides
parasitic infections must be responsible. The
eosinophilia mayberelated to chronic fungus and
otherinfections, particularly of the skin.
Complementfixation studies for parainfluenza 1, 2,

and3, respiratory syncitial, psittacosis, and Q fever

showed antibodiesto all groups of viruses except
that for Asian influenza, which probably had not
yet seriously involved the people of the Marshall
Islands. The antibodytiters appeared to be somewhatlowerin the exposed people.
Immunoelectrophoretic analysis showed neither a
paraproteinemia nora typical picture of antibody-

deficiency syndrome, but a high frequencyof in-

creases of some of the immunoglobulins was noted.
Blood volume studies with 51Cr-labeled sodium
chromate showed a significant reduction in red
cell mass and/or plasma volume. However, there

is some indication that Americansliving in the

Islands for more than | year mayalso haveslightly

lowered values. Tritiated water has been used to

establish the relationship of blood volume to lean
body mass.

Acknowledgments
The cooperation of many agencies and persons
was necessary to carry out these surveys successfully. The authors are deeply grateful for valuable
assistance to manyindividuals too numerousto
name. Weare particularly grateful to the people
of Rongelap and Utirik Atolls for their cooperation in these examinations.
Manyofficials of the Atomic Energy Commission, particularly Dr. John R. Totter and Dr.
H.D. Bruner and their staff of the Division of
Biology and Medicine, and Mr. W.A. Bonnet and
Mr. W.Streenanof the Honolulu Operations Office, were most helpful in coordination of arrangements and in supporting the surveys in every way

possible.
Weare grateful to the officials of the Departmentof the Interior, particularly Mrs. Ruth Van
Cleeve and Mrs. Elizabeth Farrington, and the

officials of the Trust Territory of the Pacific Is-

lands, including High Commissioners Mr. E.E.
Johnston and Mr. W.R. Norwood; the Director of
MedicalServices, Dr. W.M. Peck; the District Administrator for the Marshall Islands, Mr. Robert

Law; the Director of the Majuro Hospital, Dr.

John Iaman, and members ofhis staff; the Trust

Territory Representative at Kwajalein, Mr. W.M.
Ownby, and Dr. Ezra Riklon at the Ebeye Hospital; all were most helpful.
The Pacific Missile Range Facility at Kwajalein
wasof great assistance in furnishing necessary airlifts and materials. Mr. Frank Granich and others
of Global Associates at Kwajalein, Dr. ¥.C. Smith
at the Kwajalein Hospital, and Colonel D.B. Milar,
Commanding Officer, were extremely helpful.
At Brookhaven National Laboratory, contribu-

tions were made by manyindividuals in many departments, including Medical, Instrumentation
and Health Physics, Photography and Graphic
Arts, the Shipping Section, and others. We are
grateful to the following people at BNL for their
support and advice: Dr. Maurice Goldhaber, Di- *
rector; Dr. V.P. Bond, Associate Director; Dr.

J.B.H. Kuper, Chairman of the Instrumentation
and Health Physics Department; Dr. E.P. Cronkite, Chairman of the Medical Department, and
others in his Department, including Drs. D.D.

Van Slyke, J.S. Robertson, and S. Cohn, and

Messrs. A. Finn, G. Jackson, and W. J, Walsh. We
appreciate the assistance in statistical analyses
given by Mr. Keith Thompson.
In regard to advice and consultation on the thyroid pathology in the Marshallese, we are in-

debted to Drs. 8. Warren and W.A. Meissner of
the New England Deaconess Hospital; Dr. B.P.
Colcock, Lahey Clinic; and Drs. L.K. Dahl, H.L.

Atkins, and H.A. Johnson of Brookhaven National
Laboratory. Weare particularly grateful to the
nursingstaff here for their kindness and excellent

care given the Marshallese thyroid cases.
Wewishalso to thank Mrs. J. Redzinak for her
devoted secretarial assistance, and Mrs. M. Dienes

for her editorial help.

References
1. Cronxrre, E.P. et av., The Effects of lonizing Radiation
on Human Beings: A Report on the Marshallese and Americans Accidentally Exposed to Radiation Fallout anda Di1scussion ofRadiation Injury in the Human Being, AEC-TID

5358, U.S. GovernmentPrinting Office, Washington,
D.C., 1956.

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