49

The 9°Sr content of coconut crabs has not become

sufficiently lower over the years to allow lifting of

the ban on eating them.
Since we have been assigned the responsibility
of monitoring the body burdensof radioactive
materials in the Bikini people when they return to
their home island from Kili, radiochemical urine

analyses were done on 14 Bikini people in 1969.59
As expected, the levels of 187Cs and 9°Sr were
quite low. In view of the radiological decontamination being done on Bikini in anticipation of
their return, no significant increase in body burdens of the peopleis likely to occur.
SPECIAL STUDIES
Genetically Inherited Characteristics;
Blood Grouping Studies

A large body of data has been collected from
genetic studies on the Marshallese people. The results not only are of great anthropological interest
but also may show in time some possible genetic
effects of radiation exposurein future generations.
Blood grouping studies show that the Marshallese
have a relatively high B gene frequency, a high N
gene frequency, an extremely high R! genefre-

quency, and total absence of Kell and Diego

factors.°° These characteristics differ from those of
Polynesians and suggest a relationship of the
Marshallese people with Southeast Asians and
Indonesians. Haptoglobin studies showeda frequency of the Hp! gene higher than in European
populations thus far tested and consistent with
that of populations living near the equator. The
distribution of haptoglobin types showed the population to be relatively homogeneous.®! Transfernnns
in all sera were type CC, the common European
tvpe.61 B-Aminoisobutyric acid urinary levels
showed the Marshallese to be the highest excreters
of this acid of any population thusfar reported.®?.63
Levels in the exposed group were about the same
as in the unexposed group, and no correlation was
found with body burden level of radionuclides;

this indicates that there is probably no correlation

with radiation exposure. Hemoglobin types were considered normal (all had type AAg). Stckling tests

showednosickling tendency in any of the people.
Glucose-6-phosphate dehydrogenase of the red cells appeared to be normal in the Marshallese. Studies of
Gm phenotypes showed the Marshallese to have
100% Gm'4+)and nearly 100% Gm®+). There was

a complete absence of Gm* and a high frequency

of Gm-like (Gm¢).64 Serum studies for the Ag system reveal that the Rongelapese compared with
other world populations have a high frequency of

C.deB. antiserum reactors and a low frequencyof
New York antiserum reactors.65 Considerable
caution mustbe exercised in evaluating the results
of these studies on genetically inherited character-

istics because of the small number of samples
tested. The data do seem to indicate relative
homogeneity of the population andclosest kinship
with people of Southeast Asia. These data also
maybe useful as a base line, should genetic changes

appear in later generations, possibly related to

radiation exposure.

Other Laboratory Studies

Serum protein levels were generally on the high
side of normal; electrophoretic patterns showed
the increase in proteins to be due largely to an increase in the gammaglobulin fraction (see Aging
Studies). The reason for this is not apparent. Numerous chronic infections may be an explanation.
Sodium levels in the urine and food indicated
about the same consumption of NaCl as in Amer-

icans. The generally lower incidence of hypertension in the Marshallese might be related to the

fact that the former native diet was probably lower
in salt content than the present more Westernized
diet.6§ It will be interesting to see whetherthe incidence of hypertension will later increase.

Serum cholesterol levels (1957, 1959) were somewhat lowerin the exposed population than in the

comparison or Utirik populations but were in the

low normal range. No abnormally high or low

readings were noted.
Serum creatinine levels (1957) were in the normal
range with no abnormallevels noted.

Serum vitamin By. concentrations (1958, 1959)

weregenerally significantly higher than American
levels. The possibility of contamination of the
samples with bacteria producing vitamin B,2 must
be considered, since myeloproliferative and liver
diseases were not seen.
Folic acid levels were found to be somewhatlow
in the Rongelap population and probablyreflected
low dietary folic acid.
Glucosuria and elevated blood sugar were found in a
number of Rongelap people. A relatively high
incidence of diabetes is prevalent in the Marshallese people.
A survey forintestinal parasites (1958) showed
75% of the people to be infected with various

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