METHODS
DOSI tETRIC EQUATIONS

Declining continuous uptake of radioactive dietary items was mathematicall

modeled for each nuclide of concern.

The following general equations were

used

ype w

o

X.K
*iti

f, (s

Ce

i K-KE

q-q° (i Xie

E

|

.

1

(e - Qa+Kgt

Xi

1 (2 py
ii

:

Po

=() 4K, et

AD)

-(\+Kp)t
-(A+K, de
E’"
-e
i’)

Ly!

Ap? =

be ERP

,L

UU Ue/fu- a GRe

—-OA+K.)e

i)

(1)

» and

.
_ - (A+Kj)t))

(2)

o£

(Kixke -(A4K;) en (AtKgit + (A+Kg) aw)

Ki-K
1 E

(KU+A)
(K.1 +A)
E
'

+q° =

i

X.

car fire

-(A 4K; et

i

i),

(3)

where

t

= time post onset of uptake, days, .

X

= instantaneous fraction of atoma decaying per unit time, day!

P° = initial atom ingestion rate, atoms day~!,
Kj = instantaneous fraction of atoms removed from compartment i by physiological
mechanisms, day~!,
Xj; = compartment i deposition fraction,
‘

Xs = the number of atoms in compartment i relative to the number in all compart-

ments at the onset of uptake (t=0),
U

= instantaneous urine activity concentration, Bg gol,

U_

= subject urine excretion rate, & day~!,

Select target paragraph3