58
area ranges from 5 to 10pCi/liter.“?? The **Ra
content of the bone from this high thorium case was
0.087 + 0.025 pCi/g ash which correlates well with
that expected for exposure to this level of radium."*”
The **8Ra concentration in these deep well waters is
similar to that of the 226Ra.“*) Thus, theRa con-
centration in the bone of this patient will exceed that
of 73°Th and the retention of ?*Ra produced by *°*Th
decay cannot be determined from this sample.
All other ?3°Th results are less than 40 ng/g ash—
or 4{iCi/g ash. By neglecting the increase of thorium
with age and assuming a quantitative retention of
28Ra produced by thorium decay, the maximum
“28Raqa concentration would be equal to that of *°°Th
or 4fCi/g ash. This level of 7°*Ra is equal to or less
than that obtained directly from food and water so
that retention of 28Ra produced by the decay of
Compensation for Instrumental Stability. JEEL
Nuel. Set. NS-11(3), 349 (1964).
5. Lueas, H. F., Jr. Computer Program for Assay of ¢
Mixtures of Gamma-Emitting Radionuclides. .
National Laboratory Radiological Physies Divir
nual Report, July 1964 through June 1965, ANL-+
46-50.
6. Edgington, D. N., and Lucas, H. F., Jr. Neutron
tion Analysis of Samples of Biologieal and Envirai
Interest; Evaluation of the Method. Argonne \
_ Laboratory Radiological Physies Division Ann
port, July 1966 through June 1967, ANL-7360, py
. Lueas, H. F., Jr. and Edgington, D.N. Computer : 4
of Gamma-Ray Spectra. Proc. 1968 Int. Conf. on
Trends in Acitvation Analysis, October 7-11, 19
J. R. DeVoe. NBS Special Publ. No. 312 (19%
1207-1214.
8. Petrow, H. G., and Strehlow, C. D. Spectrophot:
Determination of Thorium in Bone Ash using A
III. Anal. Chem. 39, 265-267 (1967).
9. Picer, M. and Strohal, P. Determination of Thori
Uranium in Biological Materials. Anal. Chim. A
131-136 (1968).
~I
226Ra content of water from similar deep wells in this
232Th cannot be determined from these cases.)
The retention of 7**Ra produced in situ can prob-
10. Holtzman, R. B., Lueas, H. F., Jr., and Ileewicz.
The Concentration of Lead in Human Bone. This
of these have been exposed to thorium dusts at a
O
DE vice eee Ber No. * F.. Ir. r. Geol
Geologic Occ
Lueas,
and
. Emric
should be obtained.
13. Lueas, H. F., Jr. Correlation of the Natural Radio
ably be determined from industrial workers since some
.
samy
.
very much higher lev el than the normal person.‘
If possible, lung, liver, spleen, and bone samples
REFERENCES
1. Stover, B. J., Atherton, D. R., Buster, D.8., and Keller, N.
Metabolism of the *®Th Decay Series in Adult Beagle
Dogs: II. **Ra(ThX), ™?Pb(ThB), and ™%Bi(ThC).
Research in Radiobiology, U.S. Atomie Energy Commission Report COQ-119-231 (1964), pp. 110-172.
2. Edgington, D. N. Thorium and Uranium in the Natural
Environment: A Review of Present Knowledge. Argonne
National Laboratory Radiological Physies Division Annual Report, July 1964 through June 1965. ANL-7060,
pp. 73-76.
3. Edgington, D. N. The Estimation of Thorium and Uranium
at the Submicrogram Level in Bone by Neutron Activation, Int. J. Appl. Radiat. Isotopes 18, 11-18 (1967).
+. Parr, R. M., and Lueas, HW. F., Jr. A Rigorous Least Squares
’ Analysis of Complex Gamma-RaySpectra with Partial
A MODEL FOR THE REMODELING AND EXCHANGE
ADULT HUMAN BONE. PRELIMINARY REPORT*
11. Public Ground-Water Supplies in Illinois. Mhnoi-
of Natural #Ra in Ground Water in Illinois. By
Assoc. Sci. Hydrology (Holland) 8, 5-19 (1963).
of the HumanBodyto that of Its Environment:
and Retention of %¢Ra from Food and Water. A
National Laboratory Radiological Physics D
Semiannual Report, January through June 1960.
6199, pp. 55-66.
14. Krause, D. P. ™Ra (Mesothorium 1) in Illinois We
ters. Argonne National Laboratory Radiological P
Division Semiannual Report, January through Jun
ANL-6049, pp. 51-52.
15. Stehney, A. F., Radioisotopes in the Skeleton: Nat
Oceurring Radioisotopes in Man. Symp. on Radiol:
in the Biosphere, Ed. R. 8. Caldecott and L, A. 8
Center for Continuation Study, University of 3
sota, Minneapolis, 1960, pp. 366-381.
16. Albert, R., Klevin, P., Fresco, J.. Harley, J., Harr:
and Eisenbud, M. Industrial Hygiene and Medic:
vey and a Thorium Refinery. Arch. Ind. Health 11
242 (1955).
RATE DISTRIBUTIONS IN
J. H. Marshall
The International Commission of Radiological Protection
(ICRP) has requested information concerning the turnover
* This analysis was performed in connection with the work
of the (ICRP) International Commission of Radiological Protection Task Group on the Local Retention Functions of Bone
Seekers.
times of bone-seeking radioisotopes in different kinds «
man bone tissue. Maximum permissible doses to bone
heretofore been calculated assuming a uniform distrib
ICRP would nowlike to calculate doses separately for cc
and trabecular bone, for bone volumes, and for bone sul
The following model is being developed in order to ore
what experimental data are available and to provide sui